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    VGT1 vacuolar glucose transporter 1 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 821117, updated on 18-Sep-2024

    Summary

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    Official Symbol
    VGT1
    Official Full Name
    vacuolar glucose transporter 1
    Primary source
    TAIR:AT3G03090
    Locus tag
    AT3G03090
    See related
    Araport:AT3G03090
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    AtVGT1; T17B22.22; T17B22_22; vacuolar glucose transporter 1
    Summary
    Encodes a vacuolar membrane-localized glucose transporter that can also transport fructose. Mutations in these gene have effects on seed germination and time to flowering.
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    Genomic context

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    See VGT1 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    14
    Sequence:
    Chromosome: 3; NC_003074.8 (700433..704828, complement)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene NADH-ubiquinone oxidoreductase-like protein Neighboring gene Zinc-binding dehydrogenase family protein Neighboring gene NADH:ubiquinone oxidoreductase, 17.2kDa subunit Neighboring gene exportin 1B

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Identification and functional expression of the Arabidopsis thaliana vacuolar glucose transporter 1 and its role in seed germination and flowering. Aluri S, et al. Proc Natl Acad Sci U S A, 2007 Feb 13. PMID 17284600, Free PMC Article
    2. Nematode-induced changes of transporter gene expression in Arabidopsis roots. Hammes UZ, et al. Mol Plant Microbe Interact, 2005 Dec. PMID 16478044
    3. A proteomics dissection of Arabidopsis thaliana vacuoles isolated from cell culture. Jaquinod M, et al. Mol Cell Proteomics, 2007 Mar. PMID 17151019, Free PMC Article
    4. Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Salanoubat M, et al. Nature, 2000 Dec 14. PMID 11130713

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    NM_111179.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables D-glucose transmembrane transporter activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables carbohydrate transmembrane transporter activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables fructose transmembrane transporter activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within D-glucose transmembrane transport IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within fructose transmembrane transport IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within positive regulation of flower development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within response to nematode HEP PubMed 
    acts_upstream_of_or_within seed germination IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plant-type vacuole HDA PubMed 
    located_in plant-type vacuole membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane ISM
    Inferred from Sequence Model
    more info
    		  
    located_in vacuolar membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    vacuolar glucose transporter 1
    NP_186959.2
    • vacuolar glucose transporter 1 (VGT1); FUNCTIONS IN: carbohydrate transmembrane transporter activity, fructose transmembrane transporter activity, glucose transmembrane transporter activity, sugar:hydrogen symporter activity; INVOLVED IN: glucose transport, positive regulation of flower development, fructose transport, seed germination, response to nematode; LOCATED IN: plant-type vacuole membrane, vacuolar membrane, plasma membrane, membrane; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Sugar transporter, conserved site (InterPro:IPR005829), Major facilitator superfamily (InterPro:IPR020846), General substrate transporter (InterPro:IPR005828), Sugar/inositol transporter (InterPro:IPR003663), Major facilitator superfamily, general substrate transporter (InterPro:IPR016196); BEST Arabidopsis thaliana protein match is: Major facilitator superfamily protein (TAIR:AT5G17010.3); Has 40906 Blast hits to 40365 proteins in 2435 species: Archae - 733; Bacteria - 24523; Metazoa - 4373; Fungi - 7155; Plants - 2379; Viruses - 0; Other Eukaryotes - 1743 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      700433..704828 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_111179.4 → NP_186959.2  vacuolar glucose transporter 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_186959.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8L6Z8, Q9M9M8
      UniProtKB/TrEMBL
      A0A5S9X979, A0A654F3P3, A0A7G2EFE2
      Conserved Domains (1) summary
      cd17362
      Location:53 → 498
      MFS_GLUT10_12_Class3_like; Glucose transporter (GLUT) types 10 and 12, Class 3 GLUTs, and similar transporters of the Major Facilitator Superfamily
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8L6Z8.1

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