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    PUB24 E3 ubiquitin-protein ligase PUB24-like protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 820357, updated on 18-Sep-2024

    Summary

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    Official Symbol
    PUB24
    Official Full Name
    E3 ubiquitin-protein ligase PUB24-like protein
    Primary source
    TAIR:AT3G11840
    Locus tag
    AT3G11840
    See related
    Araport:AT3G11840
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    plant U-box 24
    Summary
    Encodes a U-box-domain-containing E3 ubiquitin ligase that acts as a negative regulator of PAMP-triggered immunity.
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    Genomic context

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    See PUB24 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    2
    Sequence:
    Chromosome: 3; NC_003074.8 (3736578..3738208, complement)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin superfamily protein Neighboring gene TCP-1/cpn60 chaperonin family protein Neighboring gene myosin-binding protein (Protein of unknown function, DUF593) Neighboring gene sterile alpha motif (SAM) domain protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Negative regulation of PAMP-triggered immunity by an E3 ubiquitin ligase triplet in Arabidopsis. Trujillo M, et al. Curr Biol, 2008 Sep 23. PMID 18771922
    2. Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Salanoubat M, et al. Nature, 2000 Dec 14. PMID 11130713

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Negative regulation of PAMP-triggered immunity by an E3 ubiquitin ligase (PUB22, PUB23, and PUB24) triplet in Arabidopsis. [PUB24]
      Title: Negative regulation of PAMP-triggered immunity by an E3 ubiquitin ligase triplet in Arabidopsis.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    NM_112017.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables ubiquitin protein ligase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ubiquitin-protein transferase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within defense response IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within protein autoubiquitination IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in protein ubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within respiratory burst involved in defense response IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    E3 ubiquitin-protein ligase PUB24-like protein
    NP_566402.2
    • plant U-box 24 (PUB24); FUNCTIONS IN: ubiquitin-protein ligase activity, binding; INVOLVED IN: respiratory burst involved in defense response, protein autoubiquitination, response to chitin, defense response; LOCATED IN: ubiquitin ligase complex; EXPRESSED IN: 21 plant structures; EXPRESSED DURING: 10 growth stages; CONTAINS InterPro DOMAIN/s: U box domain (InterPro:IPR003613), Armadillo-type fold (InterPro:IPR016024); BEST Arabidopsis thaliana protein match is: plant U-box 23 (TAIR:AT2G35930.1); Has 2348 Blast hits to 2308 proteins in 197 species: Archae - 0; Bacteria - 24; Metazoa - 273; Fungi - 129; Plants - 1697; Viruses - 3; Other Eukaryotes - 222 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      3736578..3738208 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_112017.4 → NP_566402.2  E3 ubiquitin-protein ligase PUB24-like protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      B9DGA6, F4J7H3, Q9SF15
      UniProtKB/TrEMBL
      A0A5S9XB66, A0A654F675
      Conserved Domains (2) summary
      smart00504
      Location:13 → 76
      Ubox; Modified RING finger domain
      cd00162
      Location:16 → 53
      RING_Ubox; U-box domain, a modified RING finger [structural motif]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9SF15.1

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