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    SIP1A small and basic intrinsic protein 1A [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 819564, updated on 18-Sep-2024

    Summary

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    Official Symbol
    SIP1A
    Official Full Name
    small and basic intrinsic protein 1A
    Primary source
    TAIR:AT3G04090
    Locus tag
    AT3G04090
    See related
    Araport:AT3G04090
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    SIP1;1; small and basic intrinsic protein 1A; T6K12.29; T6K12_29
    Summary
    Belongs to a family of plant aquaporins. Similar to yeast and radish aquaporins. Located on ER.
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    Genomic context

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    See SIP1A in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    3
    Sequence:
    Chromosome: 3; NC_003074.8 (1071984..1074244, complement)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene NAC domain containing protein 47 Neighboring gene apyrase 1 Neighboring gene AGAMOUS-like 57 Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Novel type aquaporin SIPs are mainly localized to the ER membrane and show cell-specific expression in Arabidopsis thaliana. Ishikawa F, et al. FEBS Lett, 2005 Oct 24. PMID 16223486
    2. Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Salanoubat M, et al. Nature, 2000 Dec 14. PMID 11130713

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. SIP1;1 is an aquaporin that when expressed in yeast gave water-channel activity. They are localized in ER of all tissues except dry seeds.
      Title: Novel type aquaporin SIPs are mainly localized to the ER membrane and show cell-specific expression in Arabidopsis thaliana.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    NM_111280.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables water channel activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables water channel activity IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within transmembrane transport IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within water transport IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in endoplasmic reticulum IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    small and basic intrinsic protein 1A
    NP_187059.1
    • small and basic intrinsic protein 1A (SIP1A); FUNCTIONS IN: water channel activity; INVOLVED IN: transport; LOCATED IN: endoplasmic reticulum, membrane; EXPRESSED IN: 29 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Major intrinsic protein (InterPro:IPR000425); BEST Arabidopsis thaliana protein match is: Aquaporin-like superfamily protein (TAIR:AT5G18290.2); Has 2436 Blast hits to 2434 proteins in 334 species: Archae - 16; Bacteria - 100; Metazoa - 613; Fungi - 43; Plants - 1566; Viruses - 0; Other Eukaryotes - 98 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      1071984..1074244 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_111280.5 → NP_187059.1  small and basic intrinsic protein 1A [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_187059.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q0WWC3, Q9M8W5
      UniProtKB/TrEMBL
      A0A178V5Y6, A0A5S9X900, A0A7G2EFG1
      Conserved Domains (1) summary
      cl00200
      Location:123 → 224
      MIP; Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9M8W5.1

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