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    ALDH2C4 aldehyde dehydrogenase 2C4 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 822042, updated on 18-Sep-2024

    Summary

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    Official Symbol
    ALDH2C4
    Official Full Name
    aldehyde dehydrogenase 2C4
    Primary source
    TAIR:AT3G24503
    Locus tag
    AT3G24503
    See related
    Araport:AT3G24503
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    aldehyde dehydrogenase 1A; aldehyde dehydrogenase 2C4; ALDH1A; REDUCED EPIDERMAL FLUORESCENCE1; REF1
    Summary
    Arabidopsis thaliana aldehyde dehydrogenase AtALDH1a mRNA. a sinapaldehyde dehydrogenase catalyzes both the oxidation of coniferylaldehyde and sinapaldehyde forming ferulic acid and sinapic acid, respectively
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    Genomic context

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    See ALDH2C4 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    9
    Sequence:
    Chromosome: 3; NC_003074.8 (8919560..8923296, complement)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene MUTS homolog 7 Neighboring gene ncRNA Neighboring gene multiprotein bridging factor 1C Neighboring gene ncRNA Neighboring gene uncharacterized protein Neighboring gene Defensin-like (DEFL) family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Arabidopsis thaliana REDUCED EPIDERMAL FLUORESCENCE1 gene encodes an aldehyde dehydrogenase involved in ferulic acid and sinapic acid biosynthesis. Nair RB, et al. Plant Cell, 2004 Feb. PMID 14729911, Free PMC Article
    2. Characterization of the aldehyde dehydrogenase gene families of Zea mays and Arabidopsis. Skibbe DS, et al. Plant Mol Biol, 2002 Mar-Apr. PMID 11999848
    3. Tandem affinity purification and mass spectrometric analysis of ubiquitylated proteins in Arabidopsis. Saracco SA, et al. Plant J, 2009 Jul. PMID 19292762, Free PMC Article
    4. The 14-3-3 isoforms chi and epsilon differentially bind client proteins from developing Arabidopsis seed. Swatek KN, et al. J Proteome Res, 2011 Sep 2. PMID 21766784
    5. Isolation and identification of ubiquitin-related proteins from Arabidopsis seedlings. Igawa T, et al. J Exp Bot, 2009. PMID 19429840, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_113359.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables aldehyde dehydrogenase (NAD+) activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables coniferyl-aldehyde dehydrogenase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within phenylpropanoid biosynthetic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  
    located_in cytosol HDA PubMed 

    General protein information

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    Preferred Names
    aldehyde dehydrogenase 2C4
    NP_566749.1
    • aldehyde dehydrogenase 2C4 (ALDH2C4); FUNCTIONS IN: 3-chloroallyl aldehyde dehydrogenase activity, coniferyl-aldehyde dehydrogenase activity, aldehyde dehydrogenase (NAD) activity; INVOLVED IN: phenylpropanoid biosynthetic process; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Aldehyde/histidinol dehydrogenase (InterPro:IPR016161), Aldehyde dehydrogenase (InterPro:IPR015590), Aldehyde dehydrogenase, N-terminal (InterPro:IPR016162), Aldehyde dehydrogenase, conserved site (InterPro:IPR016160); BEST Arabidopsis thaliana protein match is: aldehyde dehydrogenase 2B4 (TAIR:AT3G48000.1); Has 62142 Blast hits to 61763 proteins in 3025 species: Archae - 475; Bacteria - 35763; Metazoa - 2632; Fungi - 2134; Plants - 1679; Viruses - 0; Other Eukaryotes - 19459 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      8919560..8923296 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_113359.4 → NP_566749.1  aldehyde dehydrogenase 2C4 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_566749.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q56YU0, Q9LV57
      UniProtKB/TrEMBL
      A0A178VNA1, A0A5S9XF88, A0A654FAB0
      Conserved Domains (1) summary
      PLN02766
      Location:1 → 501
      PLN02766; coniferyl-aldehyde dehydrogenase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q56YU0.2

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