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    UGT71B6 UDP-glucosyl transferase 71B6 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 821732, updated on 18-Sep-2024

    Summary

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    Official Symbol
    UGT71B6
    Official Full Name
    UDP-glucosyl transferase 71B6
    Primary source
    TAIR:AT3G21780
    Locus tag
    AT3G21780
    See related
    Araport:AT3G21780
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    UDP-glucosyl transferase 71B6
    Summary
    Encodes a protein with UDP-glucosyl transferase activity that was shown to preferentially glucosylates abscisic acid (ABA), and not its catabolites. Moreover, UGT71B6 was shown to have a strict preference for the naturally-occurring ABA enantiomer, (+)-ABA, and not its 'unnatural' relative, (-)-ABA. This is in contrast to the other identified UGT genes catalyzing the glucosylation of ABA which were shown to accept both stereoisomers as substrates.
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    Genomic context

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    See UGT71B6 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    1
    Sequence:
    Chromosome: 3; NC_003074.8 (7674904..7676519, complement)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene UDP-Glycosyltransferase superfamily protein Neighboring gene Peroxidase superfamily protein Neighboring gene ncRNA Neighboring gene UDP-Glycosyltransferase superfamily protein Neighboring gene miscRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Use of the glucosyltransferase UGT71B6 to disturb abscisic acid homeostasis in Arabidopsis thaliana. Priest DM, et al. Plant J, 2006 May. PMID 16623908
    2. The use of abscisic acid analogues to analyse the substrate selectivity of UGT71B6, a UDP-glycosyltransferase of Arabidopsis thaliana. Priest DM, et al. FEBS Lett, 2005 Aug 15. PMID 16083885
    3. Abscisic acid uridine diphosphate glucosyltransferases play a crucial role in abscisic acid homeostasis in Arabidopsis. Dong T, et al. Plant Physiol, 2014 May. PMID 24676855, Free PMC Article
    4. Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Salanoubat M, et al. Nature, 2000 Dec 14. PMID 11130713

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. This study provides evidence that UGT71B6, an ABA uridine diphosphate glucosyltransferase (UGT), and its two closely related homologs, UGT71B7 and UGT71B8, play crucial roles in abscissic acid homeostasis.
      Title: Abscisic acid uridine diphosphate glucosyltransferases play a crucial role in abscisic acid homeostasis in Arabidopsis.
    2. Overexpression of UGT71B6 leads to massive accumulation of abscisic acid glucose ester and reduced levels of the oxidative metabolites phaseic acid and dihydrophaseic acid, but has marginal effect on levels of free abscisic acid. [UGT71B6]
      Title: Use of the glucosyltransferase UGT71B6 to disturb abscisic acid homeostasis in Arabidopsis thaliana.
    3. Substrate specificity of an Arabidopsis thaliana UDP-glycosyltransferase, UGT71B6. (UGT71B6)
      Title: The use of abscisic acid analogues to analyse the substrate selectivity of UGT71B6, a UDP-glycosyltransferase of Arabidopsis thaliana.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    General gene information

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    NM_113073.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables UDP-glycosyltransferase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables abscisic acid glucosyltransferase activity IDA
    Inferred from Direct Assay
    more info
    		  
    enables glycosyltransferase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within abscisic acid catabolic process TAS
    Traceable Author Statement
    more info
    		 PubMed 
    acts_upstream_of_or_within response to abscisic acid IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within response to osmotic stress IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within response to salt stress IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    UDP-glucosyl transferase 71B6
    NP_188815.2
    • UDP-glucosyl transferase 71B6 (UGT71B6); FUNCTIONS IN: UDP-glycosyltransferase activity, transferase activity, transferring glycosyl groups, abscisic acid glucosyltransferase activity; INVOLVED IN: response to salt stress, response to abscisic acid stimulus, response to osmotic stress, abscisic acid catabolic process; LOCATED IN: membrane; EXPRESSED IN: stem, rosette leaf, cultured cell, stamen, leaf; EXPRESSED DURING: 4 anthesis; CONTAINS InterPro DOMAIN/s: UDP-glucuronosyl/UDP-glucosyltransferase (InterPro:IPR002213); BEST Arabidopsis thaliana protein match is: UDP-Glycosyltransferase superfamily protein (TAIR:AT3G21790.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      7674904..7676519 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_113073.3 → NP_188815.2  UDP-glucosyl transferase 71B6 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_188815.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A1L4W4, Q9LSY6
      UniProtKB/TrEMBL
      A0A654F9G4, W8Q353
      Conserved Domains (1) summary
      PLN02554
      Location:1 → 473
      PLN02554; UDP-glycosyltransferase family protein
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9LSY6.1

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