HMG high mobility group [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Official Symbol: HMG
Official Full Name: high mobility group
Primary source: TAIR:AT3G28730
Locus tag: AT3G28730
See related: Araport:AT3G28730
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: ATHMG; high mobility group; NFD; NUCLEOSOME/CHROMATIN ASSEMBLY FACTOR D; SSRP1
Summary: encodes a component of the FAcilitates Chromatin Transcription (FACT) complex, SSRP1. Along with STP16 binds to the promoter of FLC.
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Genomic context

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See HMG in Genome Data Viewer

Location:: chromosome: 3

Exon count:: 16

Sequence:: Chromosome: 3; NC_003074.8 (10784888..10788729)

Chromosome 3 - NC_003074.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003074.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

subunit of the histone chaperone FACT that is required for seed dormancy
Title: The SSRP1 subunit of the histone chaperone FACT is required for seed dormancy in Arabidopsis.
FACT (SSRP1 and SPT16) is a novel factor required for the accumulation of anthocyanins in response to light-induction.
Title: The Arabidopsis histone chaperone FACT is required for stress-induced expression of anthocyanin biosynthetic genes.
Active DNA demethylation by DEMETER requires SSRP1 function through a distinctly different process from direct DNA methylation control.
Title: HMG domain containing SSRP1 is required for DNA demethylation and genomic imprinting in Arabidopsis.
SPT16 and SSRP1 are critically involved in the regulation of leaf growth, flowering time and seed production, and interact with HUB1/2.
Title: The transcript elongation factor FACT affects Arabidopsis vegetative and reproductive development and genetically interacts with HUB1/2.

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Pathways from PubChem

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Homology

Orthologs from OrthoDB

NM_113794.4

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables DNA-binding transcription factor activity	ISS Inferred from Sequence or Structural Similarity more info	PubMed
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
involved_in karyogamy	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in polar nucleus fusion	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within vegetative to reproductive phase transition of meristem	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
part_of FACT complex	IDA Inferred from Direct Assay more info	PubMed
located_in euchromatin	IDA Inferred from Direct Assay more info	PubMed
located_in nucleus	IDA Inferred from Direct Assay more info	PubMed
located_in nucleus	ISM Inferred from Sequence Model more info

General protein information

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Preferred Names: high mobility group

NP_189515.1

high mobility group (HMG); CONTAINS InterPro DOMAIN/s: Structure-specific recognition protein (InterPro:IPR000969), High mobility group, superfamily (InterPro:IPR009071), High mobility group, HMG1/HMG2 (InterPro:IPR000910); BEST Arabidopsis thaliana protein match is: high mobility group B1 (TAIR:AT3G51880.2); Has 8066 Blast hits to 7188 proteins in 653 species: Archae - 0; Bacteria - 14; Metazoa - 5623; Fungi - 822; Plants - 671; Viruses - 15; Other Eukaryotes - 921 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003074.8 Reference assembly

Range

10784888..10788729

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_113794.4 → NP_189515.1 high mobility group [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_189515.1

Status: REVIEWED

UniProtKB/Swiss-Prot

C0Z265, Q05153, Q56X23, Q9LHA2

UniProtKB/TrEMBL

A0A178VCP0, A0A5S9XGK5

Conserved Domains (2) summary

COG5165
Location:7 → 440

POB3; Nucleosome-binding factor SPN, POB3 subunit [Transcription / DNA replication, recombination, and repair / Chromatin structure and dynamics]

cd01390
Location:564 → 627

HMGB-UBF_HMG-box; class II and III members of the HMG-box superfamily of DNA-binding proteins. These proteins bind the minor groove of DNA in a non-sequence specific fashion and contain two or more tandem HMG boxes. Class II members include non-histone chromosomal ...