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    SHM6 serine hydroxymethyltransferase 6 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 838807, updated on 18-Sep-2024

    Summary

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    Official Symbol
    SHM6
    Official Full Name
    serine hydroxymethyltransferase 6
    Primary source
    TAIR:AT1G22020
    Locus tag
    AT1G22020
    See related
    Araport:AT1G22020
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F2E2.7; F2E2_7; serine hydroxymethyltransferase 6
    Summary
    Encodes a putative serine hydroxymethyltransferase.
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    Genomic context

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    See SHM6 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    5
    Sequence:
    Chromosome: 1; NC_003070.9 (7754281..7758029)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Galactosyltransferase family protein Neighboring gene BPS1-like protein Neighboring gene miscRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Arabidopsis thaliana serine hydroxymethyltransferases: functions, structures, and perspectives. Nogués I, et al. Plant Physiol Biochem, 2022 Sep 15. PMID 35947902
    2. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    NM_102052.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables glycine hydroxymethyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables pyridoxal phosphate binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in glycine biosynthetic process from serine IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in tetrahydrofolate interconversion IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    serine hydroxymethyltransferase 6
    NP_173621.1
    • serine hydroxymethyltransferase 6 (SHM6); FUNCTIONS IN: pyridoxal phosphate binding, glycine hydroxymethyltransferase activity, catalytic activity; INVOLVED IN: glycine metabolic process, L-serine metabolic process; LOCATED IN: cellular_component unknown; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Pyridoxal phosphate-dependent transferase, major domain (InterPro:IPR015424), Serine hydroxymethyltransferase, pyridoxal phosphate binding site (InterPro:IPR019798), Pyridoxal phosphate-dependent transferase, major region, subdomain 1 (InterPro:IPR015421), Serine hydroxymethyltransferase (InterPro:IPR001085); BEST Arabidopsis thaliana protein match is: serine hydroxymethyltransferase 7 (TAIR:AT1G36370.1); Has 11545 Blast hits to 11518 proteins in 2846 species: Archae - 258; Bacteria - 6402; Metazoa - 340; Fungi - 287; Plants - 348; Viruses - 6; Other Eukaryotes - 3904 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      7754281..7758029
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001332533.1 → NP_001323098.1  serine hydroxymethyltransferase 6 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9LM59
      UniProtKB/TrEMBL
      A0A178WEU9, A0A5S9VH45, A0A654EMS1, A0A7G2DUS2
      Conserved Domains (1) summary
      PLN02271
      Location:1 → 599
      PLN02271; serine hydroxymethyltransferase

    2. NM_102052.3 → NP_173621.1  serine hydroxymethyltransferase 6 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_173621.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9LM59
      UniProtKB/TrEMBL
      A0A178WEU9, A0A5S9VH45, A0A654EMS1, A0A7G2DUS2
      Conserved Domains (1) summary
      PLN02271
      Location:1 → 599
      PLN02271; serine hydroxymethyltransferase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9LM59.1

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