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    CRL2 NAD(P)-binding Rossmann-fold superfamily protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 817926, updated on 18-Sep-2024

    Summary

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    Official Symbol
    CRL2
    Official Full Name
    NAD(P)-binding Rossmann-fold superfamily protein
    Primary source
    TAIR:AT2G33600
    Locus tag
    AT2G33600
    See related
    Araport:AT2G33600
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    AtCRL2; CCR(Cinnamoyl coA:NADP oxidoreductase)-like 2; F4P9.37; F4P9_37
    Summary
    Encodes a protein with homology to members of the dihydroflavonol-4-reductase (DFR) superfamily. Its expression pattern suggests that AtCRL2 is involved in the synthesis and/or maintenance of vascular tissue.
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    Genomic context

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    See CRL2 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    6
    Sequence:
    Chromosome: 2; NC_003071.7 (14226668..14228742)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene subtilisin-like protease Neighboring gene NAD(P)-binding Rossmann-fold superfamily protein Neighboring gene switch subunit 3 Neighboring gene AT hook motif DNA-binding family protein Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Proteome-wide screens for small ubiquitin-like modifier (SUMO) substrates identify Arabidopsis proteins implicated in diverse biological processes. Elrouby N, et al. Proc Natl Acad Sci U S A, 2010 Oct 5. PMID 20855607, Free PMC Article
    2. Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Lin X, et al. Nature, 1999 Dec 16. PMID 10617197

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_128920.3

    Gene Ontology Provided by TAIR

    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    NAD(P)-binding Rossmann-fold superfamily protein
    NP_180918.1
    • NAD(P)-binding Rossmann-fold superfamily protein; FUNCTIONS IN: coenzyme binding, binding, cinnamoyl-CoA reductase activity, catalytic activity; INVOLVED IN: lignin biosynthetic process, cellular metabolic process, metabolic process; EXPRESSED IN: 21 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: NAD-dependent epimerase/dehydratase (InterPro:IPR001509), NAD(P)-binding domain (InterPro:IPR016040); BEST Arabidopsis thaliana protein match is: NAD(P)-binding Rossmann-fold superfamily protein (TAIR:AT2G33590.1); Has 13587 Blast hits to 13572 proteins in 2016 species: Archae - 236; Bacteria - 6094; Metazoa - 449; Fungi - 930; Plants - 2647; Viruses - 67; Other Eukaryotes - 3164 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      14226668..14228742
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_128920.3 → NP_180918.1  NAD(P)-binding Rossmann-fold superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_180918.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178VVW0, A0A7G2EH57, O22810
      Conserved Domains (1) summary
      cd08958
      Location:9 → 298
      FR_SDR_e; flavonoid reductase (FR), extended (e) SDRs
    Nucleotide Protein
    Heading Accession and Version

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