DES-1-LIKE fatty acid desaturase family protein [Arabidopsis thaliana (thale cress)] - Gene

Summary

Official Symbol: DES-1-LIKE
Official Full Name: fatty acid desaturase family protein
Primary source: TAIR:AT4G04930
Locus tag: AT4G04930
See related: Araport:AT4G04930
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: DES-1-LIKE TRANSMEMBRANE PROTEIN; T1J1.1; T1J1_1
Summary: Encodes a sphingolipid delta4-desaturase, involved in sphingolipid biosynthesis. Specifically expressed in floral tissues. Knockout mutants were devoid of sphinga-4,8-dienine in floral tissues.
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Chromosome 4 - NC_003075.7 Genomic Context describing neighboring genes

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Arabidopsis insertion mutants disrupted in the sphingolipid delta4-desaturase At4g04930 were isolated and found to be phenotypically normal.
Title: Functional characterization of a higher plant sphingolipid Delta4-desaturase: defining the role of sphingosine and sphingosine-1-phosphate in Arabidopsis.

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NM_116731.4

Function	Evidence Code	Pubs
enables sphingolipid delta-4 desaturase activity	IGI Inferred from Genetic Interaction more info	PubMed
enables sphingolipid delta-4 desaturase activity	IMP Inferred from Mutant Phenotype more info	PubMed

Process	Evidence Code	Pubs
acts_upstream_of_or_within sphingolipid biosynthetic process	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
is_active_in cellular_component	ND No biological Data available more info

NP_192402.1

DES-1-LIKE; FUNCTIONS IN: oxidoreductase activity, sphingolipid delta-4 desaturase activity; INVOLVED IN: sphingolipid biosynthetic process; LOCATED IN: integral to membrane; EXPRESSED IN: 10 plant structures; EXPRESSED DURING: L mature pollen stage, M germinated pollen stage, 4 anthesis, C globular stage, petal differentiation and expansion stage; CONTAINS InterPro DOMAIN/s: Sphingolipid delta4-desaturase, N-terminal (InterPro:IPR013866), Fatty acid desaturase, type 1 (InterPro:IPR005804), Sphingolipid delta4-desaturase (InterPro:IPR011388); Has 703 Blast hits to 697 proteins in 257 species: Archae - 0; Bacteria - 174; Metazoa - 227; Fungi - 120; Plants - 36; Viruses - 3; Other Eukaryotes - 143 (source: NCBI BLink).

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