Peptidase M20/M25/M40 family protein [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Official Full Name: Peptidase M20/M25/M40 family protein
Primary source: TAIR:AT4G17830
Locus tag: AT4G17830
See related: Araport:AT4G17830
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
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Genomic context

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See in Genome Data Viewer

Location:: chromosome: 4

Exon count:: 9

Sequence:: Chromosome: 4; NC_003075.7 (9915813..9918243)

Chromosome 4 - NC_003075.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003075.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Data suggest that N-acetylornithine deacetylase (AT4G17830; AtNAOD) participates in ornithine (Orn) and polyamines (PA) homeostasis, contributing to maintain an optimal nitrogen:carbon (N:C) balance during reproductive development.
Title: The Arabidopsis N-Acetylornithine Deacetylase Controls Ornithine Biosynthesis via a Linear Pathway with Downstream Effects on Polyamine Levels.
Study demonstrates a link between putative N-acetylornithine deacetylase (AtNAOD) activity and the cellular levels of ornithine and PAs; it also provides evidence of a role for AtNAOD in flowering and in fruit setting. [AtNAOD]
Title: Involvement of the Putative N-Acetylornithine Deacetylase from Arabidopsis thaliana in Flowering and Fruit Development.

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Pathways from PubChem

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Homology

Orthologs from OrthoDB

NM_117892.5

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables acetylornithine deacetylase activity	IDA Inferred from Direct Assay more info	PubMed
enables acetylornithine deacetylase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in L-arginine biosynthetic process	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within ornithine biosynthetic process	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in chloroplast	ISM Inferred from Sequence Model more info
located_in cytosol	HDA more info	PubMed

General protein information

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Preferred Names: Peptidase M20/M25/M40 family protein

NP_001190758.1

Peptidase M20/M25/M40 family protein; FUNCTIONS IN: metallopeptidase activity, hydrolase activity; INVOLVED IN: proteolysis, metabolic process; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Peptidase M20 (InterPro:IPR002933), Peptidase M20, dimerisation (InterPro:IPR011650).

NP_193517.3

Peptidase M20/M25/M40 family protein; FUNCTIONS IN: metallopeptidase activity, hydrolase activity; INVOLVED IN: proteolysis, metabolic process; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Peptidase M20 (InterPro:IPR002933), Peptidase M20, dimerisation (InterPro:IPR011650); Has 6221 Blast hits to 6219 proteins in 1645 species: Archae - 204; Bacteria - 4419; Metazoa - 218; Fungi - 167; Plants - 78; Viruses - 0; Other Eukaryotes - 1135 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003075.7 Reference assembly

Range

9915813..9918243

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_001203829.1 → NP_001190758.1 Peptidase M20/M25/M40 family protein [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_001190758.1

Status: REVIEWED

UniProtKB/TrEMBL

A0A654FQC3, F4JPZ7

Conserved Domains (2) summary

cd08012
Location:15 → 442

M20_ArgE-related; M20 Peptidases with simlarity to acetylornithine deacetylases

pfam01546
Location:101 → 441

Peptidase_M20; Peptidase family M20/M25/M40
NM_117892.5 → NP_193517.3 Peptidase M20/M25/M40 family protein [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_193517.3

Status: REVIEWED

UniProtKB/Swiss-Prot

O23622, O49682, Q9C5C4

UniProtKB/TrEMBL

A0A178UY21, A0A5S9XTH6, A0A654FQC3

Conserved Domains (1) summary

cd08012
Location:15 → 437

M20_ArgE-related; M20 Peptidases with similarity to acetylornithine deacetylases