NLP7 NIN like protein 7 [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Official Symbol: NLP7
Official Full Name: NIN like protein 7
Primary source: TAIR:AT4G24020
Locus tag: AT4G24020
See related: Araport:AT4G24020
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: NIN like protein 7; T19F6.10; T19F6_10
Summary: Encodes NIN Like Protein 7 (NLP7). Modulates nitrate sensing and metabolism. Mutants of NLP7 show features of nitrogen-starved plants and are tolerant to drought stress. Localized in the nucleus and functions as a putative transcription factor.
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Genomic context

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See NLP7 in Genome Data Viewer

Location:: chromosome: 4

Exon count:: 5

Sequence:: Chromosome: 4; NC_003075.7 (12479528..12484049)

Chromosome 4 - NC_003075.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003075.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

The NIN-LIKE PROTEIN 7 transcription factor modulates auxin pathways to regulate root cap development in Arabidopsis.
Title: The NIN-LIKE PROTEIN 7 transcription factor modulates auxin pathways to regulate root cap development in Arabidopsis.
NIN-like protein 7 transcription factor is a plant nitrate sensor.
Title: NIN-like protein 7 transcription factor is a plant nitrate sensor.
NIN-like protein7 and PROTEOLYSIS6 functional interaction enhances tolerance to sucrose, ABA, and submergence.
Title: NIN-like protein7 and PROTEOLYSIS6 functional interaction enhances tolerance to sucrose, ABA, and submergence.
NIN-like protein 7 promotes nitrate-mediated lateral root development by activating transcription of TRYPTOPHAN AMINOTRANSFERASE RELATED 2.
Title: NIN-like protein 7 promotes nitrate-mediated lateral root development by activating transcription of TRYPTOPHAN AMINOTRANSFERASE RELATED 2.
NLP7 regulates dynamic and early nitrogen responses, and where it fits in the temporal hierarchy of the nitrogen transcriptional network.
Title: Transient genome-wide interactions of the master transcription factor NLP7 initiate a rapid nitrogen-response cascade.
NLP7 control of root cap cell release is largely independent of gravity sensing and root cap cell identity.
Title: Further insights into the role of NIN-LIKE PROTEIN 7 (NLP7) in root cap cell release.
Results demonstrate that NLP7 significantly improves plant growth under both nitrogen-poor and -rich conditions by coordinately enhancing nitrogen and carbon assimilation and sheds light on crop improvement.
Title: Overexpression of Arabidopsis NLP7 improves plant growth under both nitrogen-limiting and -sufficient conditions by enhancing nitrogen and carbon assimilation.
TCP20 and NLP6/NLP7 transcription factors control plant responses to nitrate availability.
Title: Interacting TCP and NLP transcription factors control plant responses to nitrate availability.
NLP7 expression maintains pectin and cellulose levels in the root and represses the expression of CEL5, XTH5, PL, SMB, and BRN1/2, thereby preventing single cell border-like cell release.
Title: The Transcription Factor NIN-LIKE PROTEIN7 Controls Border-Like Cell Release.
nitrate-coupled CPK signalling phosphorylates conserved NIN-LIKE PROTEIN (NLP) transcription factors to specify the reprogramming of gene sets for downstream transcription factors, transporters, nitrogen assimilation, carbon/nitrogen metabolism, redox, signalling, hormones and proliferation
Title: Discovery of nitrate-CPK-NLP signalling in central nutrient-growth networks.

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Homology

Orthologs from OrthoDB

NM_001341638.1

Supported by ESTs:

NM_118534.6

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables DNA-binding transcription factor activity	IEA Inferred from Electronic Annotation more info
enables DNA-binding transcription factor activity	ISS Inferred from Sequence or Structural Similarity more info	PubMed
enables cis-regulatory region sequence-specific DNA binding	IPI Inferred from Physical Interaction more info	PubMed
enables core promoter sequence-specific DNA binding	IPI Inferred from Physical Interaction more info	PubMed
enables transcription cis-regulatory region binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
acts_upstream_of_or_within nitrate assimilation	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within response to nitrate	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within response to water deprivation	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within stomatal movement	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in nucleus	IDA Inferred from Direct Assay more info	PubMed
located_in nucleus	ISM Inferred from Sequence Model more info

General protein information

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Preferred Names: NIN like protein 7

NP_194133.1

NIN like protein 7 (NLP7); CONTAINS InterPro DOMAIN/s: Octicosapeptide/Phox/Bem1p (InterPro:IPR000270), Plant regulator RWP-RK (InterPro:IPR003035); BEST Arabidopsis thaliana protein match is: Plant regulator RWP-RK family protein (TAIR:AT1G64530.1); Has 724 Blast hits to 614 proteins in 51 species: Archae - 0; Bacteria - 2; Metazoa - 5; Fungi - 15; Plants - 632; Viruses - 0; Other Eukaryotes - 70 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003075.7 Reference assembly

Range

12479528..12484049

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_118534.6 → NP_194133.1 NIN like protein 7 [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_194133.1

Status: REVIEWED

UniProtKB/Swiss-Prot

O22987, Q84TH9

UniProtKB/TrEMBL

A0A178V1Z0, A0A5S9XVB4

Conserved Domains (2) summary

cd06407
Location:864 → 944

PB1_NLP; A PB1 domain is present in NIN like proteins (NLP), a key enzyme in a process of establishment of symbiosis betweeen legumes and nitrogen fixing bacteria (Rhizobium). The PB1 domain is a modular domain mediating specific protein-protein interaction which ...

pfam02042
Location:591 → 639

RWP-RK; RWP-RK domain
NM_001341638.1 → NP_001328405.1 NIN like protein 7 [Arabidopsis thaliana]

Status: REVIEWED

UniProtKB/TrEMBL

A0A1P8B4J4