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    DNAJ heat shock N-terminal domain-containing protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 830529, updated on 18-Sep-2024

    Summary

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    Official Full Name
    DNAJ heat shock N-terminal domain-containing protein
    Primary source
    TAIR:AT5G06410
    Locus tag
    AT5G06410
    See related
    Araport:AT5G06410
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    MHF15.7; MHF15_7
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    Genomic context

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    Location:
    chromosome: 5
    Exon count:
    6
    Sequence:
    Chromosome: 5; NC_003076.8 (1959367..1961158, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene FASCICLIN-like arabinogalactan protein 17 precursor Neighboring gene Pentatricopeptide repeat (PPR) superfamily protein Neighboring gene ncRNA Neighboring gene Zinc finger (CCCH-type/C3HC4-type RING finger) family protein Neighboring gene Thioredoxin superfamily protein Neighboring gene polyketide cyclase/dehydrase/lipid transport superfamily protein Neighboring gene Polynucleotidyl transferase, ribonuclease H-like superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Altered levels of AtHSCB disrupts iron translocation from roots to shoots. Leaden L, et al. Plant Mol Biol, 2016 Nov. PMID 27655366
    2. The mitochondrial proteins AtHscB and AtIsu1 involved in Fe-S cluster assembly interact with the Hsp70-type chaperon AtHscA2 and modulate its catalytic activity. Leaden L, et al. Mitochondrion, 2014 Nov. PMID 25462017
    3. Dual localized AtHscB involved in iron sulfur protein biogenesis in Arabidopsis. Xu XM, et al. PLoS One, 2009 Oct 29. PMID 19865480, Free PMC Article
    4. Evidence for network evolution in an Arabidopsis interactome map. Arabidopsis Interactome Mapping Consortium. Science, 2011 Jul 29. PMID 21798944, Free PMC Article
    5. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Results suggest that AtHscA2 in cooperation with AtIsu1 and AtHscB play an important role in the regulation of the Fe-S cluster assembly pathway in plant mitochondria.
      Title: The mitochondrial proteins AtHscB and AtIsu1 involved in Fe-S cluster assembly interact with the Hsp70-type chaperon AtHscA2 and modulate its catalytic activity.
    2. AtHscB together with AtHscA and AtIscU1 plays an important role in the biogenesis of iron-sulfur proteins in both mitochondria and the cytosol. [HscB]
      Title: Dual localized AtHscB involved in iron sulfur protein biogenesis in Arabidopsis.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_120724.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables ATPase activator activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein-folding chaperone binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in [2Fe-2S] cluster assembly IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in iron-sulfur cluster assembly IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within multicellular organismal-level iron ion homeostasis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in protein complex oligomerization IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in mitochondrion IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in mitochondrion ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    DNAJ heat shock N-terminal domain-containing protein
    NP_196259.2
    • DNAJ heat shock N-terminal domain-containing protein; FUNCTIONS IN: heat shock protein binding, chaperone binding; INVOLVED IN: protein folding; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Heat shock cognate protein B, C-terminal oligomerisation (InterPro:IPR009073), Heat shock protein DnaJ, N-terminal (InterPro:IPR001623), Co-chaperone Hsc20 (InterPro:IPR004640); Has 1884 Blast hits to 1884 proteins in 890 species: Archae - 0; Bacteria - 1464; Metazoa - 116; Fungi - 101; Plants - 38; Viruses - 0; Other Eukaryotes - 165 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      1959367..1961158 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_120724.3 → NP_196259.2  DNAJ heat shock N-terminal domain-containing protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_196259.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8L7K4, Q9FNG7
      UniProtKB/TrEMBL
      A0A5S9Y2R4, A0A654FZC1
      Conserved Domains (1) summary
      PRK05014
      Location:93 → 231
      hscB; co-chaperone HscB; Provisional
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8L7K4.1

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