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    BON2 Calcium-dependent phospholipid-binding Copine family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 830621, updated on 18-Sep-2024

    Summary

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    Official Symbol
    BON2
    Official Full Name
    Calcium-dependent phospholipid-binding Copine family protein
    Primary source
    TAIR:AT5G07300
    Locus tag
    AT5G07300
    See related
    Araport:AT5G07300
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    BONZAI 2; T2I1.10; T2I1_10
    Summary
    Encodes a copine-like protein, which is a member of a newly identified class of calcium-dependent, phospholipid binding proteins that are present in a wide range of organisms.
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    Genomic context

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    See BON2 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    16
    Sequence:
    Chromosome: 5; NC_003076.8 (2299725..2303268)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene MEI2-like 4 Neighboring gene Integrase-type DNA-binding superfamily protein Neighboring gene tRNA-Tyr

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Arabidopsis BAP1 and BAP2 genes are general inhibitors of programmed cell death. Yang H, et al. Plant Physiol, 2007 Sep. PMID 17631528, Free PMC Article
    2. Targeted interactomics reveals a complex core cell cycle machinery in Arabidopsis thaliana. Van Leene J, et al. Mol Syst Biol, 2010 Aug 10. PMID 20706207, Free PMC Article
    3. A high content in lipid-modified peripheral proteins and integral receptor kinases features in the arabidopsis plasma membrane proteome. Marmagne A, et al. Mol Cell Proteomics, 2007 Nov. PMID 17644812
    4. Arabidopsis plasmodesmal proteome. Fernandez-Calvino L, et al. PLoS One, 2011 Apr 20. PMID 21533090, Free PMC Article
    5. Evidence for network evolution in an Arabidopsis interactome map. Arabidopsis Interactome Mapping Consortium. Science, 2011 Jul 29. PMID 21798944, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_120812.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables calcium-dependent phospholipid binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables calcium-dependent phospholipid binding NAS
    Non-traceable Author Statement
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane HDA PubMed 
    located_in plasmodesma HDA PubMed 

    General protein information

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    Preferred Names
    Calcium-dependent phospholipid-binding Copine family protein
    NP_568180.1
    • BONZAI 2 (BON2); FUNCTIONS IN: calcium-dependent phospholipid binding; LOCATED IN: plasma membrane; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: C2 membrane targeting protein (InterPro:IPR018029), C2 calcium/lipid-binding domain, CaLB (InterPro:IPR008973), Copine (InterPro:IPR010734), C2 calcium-dependent membrane targeting (InterPro:IPR000008), von Willebrand factor, type A (InterPro:IPR002035); BEST Arabidopsis thaliana protein match is: DCD (Development and Cell Death) domain protein (TAIR:AT5G61910.4); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      2299725..2303268
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_120812.4 → NP_568180.1  Calcium-dependent phospholipid-binding Copine family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_568180.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q5S1W2, Q94EW4, Q9LY30
      UniProtKB/TrEMBL
      A0A178UEP3, A0A5S9Y262
      Conserved Domains (3) summary
      cd04047
      Location:197 → 300
      C2B_Copine; C2 domain second repeat in Copine
      cd04048
      Location:47 → 164
      C2A_Copine; C2 domain first repeat in Copine
      cd01459
      Location:315 → 567
      vWA_copine_like; VWA Copine: Copines are phospholipid-binding proteins originally identified in paramecium. They are found in human and orthologues have been found in C. elegans and Arabidopsis Thaliana. None have been found in D. Melanogaster or S. Cereviciae. ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5S1W2.2

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