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    transcription regulator NOT2/NOT3/NOT5 family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 831941, updated on 18-Sep-2024

    Summary

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    Official Full Name
    transcription regulator NOT2/NOT3/NOT5 family protein
    Primary source
    TAIR:AT5G18230
    Locus tag
    AT5G18230
    See related
    Araport:AT5G18230
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    MRG7.19; MRG7_19
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    Genomic context

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    Location:
    chromosome: 5
    Exon count:
    17
    Sequence:
    Chromosome: 5; NC_003076.8 (6021379..6027299, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene miscRNA Neighboring gene NAD(P)-binding Rossmann-fold superfamily protein Neighboring gene O-Glycosyl hydrolases family 17 protein Neighboring gene ncRNA Neighboring gene myb-related protein 1 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Capturing the phosphorylation and protein interaction landscape of the plant TOR kinase. Van Leene J, et al. Nat Plants, 2019 Mar. PMID 30833711
    2. Mapping the signaling network of BIN2 kinase using TurboID-mediated biotin labeling and phosphoproteomics. Kim TW, et al. Plant Cell, 2023 Mar 15. PMID 36660928, Free PMC Article
    3. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_001161244.1
    NM_001343540.1
    NM_001343541.1
    NM_121828.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of CCR4-NOT core complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    transcription regulator NOT2/NOT3/NOT5 family protein
    NP_001154716.1
    • transcription regulator NOT2/NOT3/NOT5 family protein; FUNCTIONS IN: transcription regulator activity; INVOLVED IN: negative regulation of transcription, regulation of transcription; LOCATED IN: nucleus; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: NOT2/NOT3/NOT5 (InterPro:IPR007282), CCR4-NOT complex, subunit 3/ 5 (InterPro:IPR012270), Not CCR4-Not complex component, N-terminal (InterPro:IPR007207); BEST Arabidopsis thaliana protein match is: NOT2 / NOT3 / NOT5 family (TAIR:AT1G07705.2); Has 3972 Blast hits to 2940 proteins in 410 species: Archae - 18; Bacteria - 365; Metazoa - 1231; Fungi - 912; Plants - 255; Viruses - 11; Other Eukaryotes - 1180 (source: NCBI BLink).
    NP_568361.1
    • transcription regulator NOT2/NOT3/NOT5 family protein; FUNCTIONS IN: transcription regulator activity; INVOLVED IN: negative regulation of transcription, regulation of transcription; LOCATED IN: nucleus; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: NOT2/NOT3/NOT5 (InterPro:IPR007282), CCR4-NOT complex, subunit 3/ 5 (InterPro:IPR012270), Not CCR4-Not complex component, N-terminal (InterPro:IPR007207); BEST Arabidopsis thaliana protein match is: NOT2 / NOT3 / NOT5 family (TAIR:AT1G07705.2); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      6021379..6027299 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_121828.5 → NP_568361.1  transcription regulator NOT2/NOT3/NOT5 family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_568361.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A654G2A7, F4JWJ6, Q94JY7
      Conserved Domains (2) summary
      COG5665
      Location:12 → 839
      COG5665; CCR4-NOT transcriptional regulation complex, NOT5 subunit [Transcription]
      pfam04065
      Location:3 → 233
      Not3; Not1 N-terminal domain, CCR4-Not complex component

    2. NM_001343541.1 → NP_001330084.1  transcription regulator NOT2/NOT3/NOT5 family protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8B9R0, Q94JY7

    3. NM_001161244.1 → NP_001154716.1  transcription regulator NOT2/NOT3/NOT5 family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001154716.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      F4JWJ7, Q94JY7
      Conserved Domains (3) summary
      COG5665
      Location:12 → 841
      COG5665; CCR4-NOT transcriptional regulation complex, NOT5 subunit [Transcription]
      pfam04065
      Location:3 → 235
      Not3; Not1 N-terminal domain, CCR4-Not complex component
      pfam04153
      Location:704 → 837
      NOT2_3_5; NOT2 / NOT3 / NOT5 family

    4. NM_001343540.1 → NP_001330085.1  transcription regulator NOT2/NOT3/NOT5 family protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8B9Q7, Q94JY7
    Nucleotide Protein
    Heading Accession and Version

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