U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    AHP3 histidine-containing phosphotransmitter 3 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 833930, updated on 18-Sep-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    AHP3
    Official Full Name
    histidine-containing phosphotransmitter 3
    Primary source
    TAIR:AT5G39340
    Locus tag
    AT5G39340
    See related
    Araport:AT5G39340
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ARABIDOPSIS THALIANA HISTIDINE-CONTAINING PHOSPHOTRANSMITTER 2; ATHP2; HIS-ASP PHOSPHOTRANSFER SIGNAL TRANSDUCER; histidine-containing phosphotransmitter 3; MUL8.20; MUL8_20
    Summary
    Encodes AHP3, one of the six Arabidopsis thaliana histidine phosphotransfer proteins (AHPs) involved in Histidine (His)-to-Aspartate (Asp) phosphorelay signal transduction. AHPs function as redundant positive regulators of cytokinin signaling. Members of the AHP gene family include: AT3G21510 (AHP1), AT3G29350 (AHP2), AT5G39340 (AHP3), AT3G16360 (AHP4), AT1G03430 (AHP5) and AT1G80100 (AHP6).
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See AHP3 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    7
    Sequence:
    Chromosome: 5; NC_003076.8 (15748731..15750891)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene UDP-glucose 6-dehydrogenase family protein Neighboring gene transmembrane protein, putative (DUF1163) Neighboring gene Tetratricopeptide repeat (TPR)-like superfamily protein Neighboring gene EID1-like 2 Neighboring gene Defensin-like (DEFL) family protein

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Targeted in vivo inhibition of specific protein-protein interactions using recombinant antibodies. Zábrady M, et al. PLoS One, 2014. PMID 25299686, Free PMC Article
    2. Arabidopsis AHP2, AHP3, and AHP5 histidine phosphotransfer proteins function as redundant negative regulators of drought stress response. Nishiyama R, et al. Proc Natl Acad Sci U S A, 2013 Mar 19. PMID 23487796, Free PMC Article
    3. His-Asp phosphotransfer possibly involved in the nitrogen signal transduction mediated by cytokinin in maize: molecular cloning of cDNAs for two-component regulatory factors and demonstration of phosphotransfer activity in vitro. Sakakibara H, et al. Plant Mol Biol, 1999 Nov. PMID 10608665
    4. Arabidopsis response Regulator1 and Arabidopsis histidine phosphotransfer Protein2 (AHP2), AHP3, and AHP5 function in cold signaling. Jeon J, et al. Plant Physiol, 2013 Jan. PMID 23124324, Free PMC Article
    5. Compilation and characterization of histidine-containing phosphotransmitters implicated in His-to-Asp phosphorelay in plants: AHP signal transducers of Arabidopsis thaliana. Suzuki T, et al. Biosci Biotechnol Biochem, 2000 Nov. PMID 11193423

    See all (24) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Our selection method was successfully used to develop a recombinant antibody inhibiting the interaction of AHP3 with such of its upstream interaction partners as the receiver domain of CKI 1.
      Title: Targeted in vivo inhibition of specific protein-protein interactions using recombinant antibodies.
    2. ARR1 mediates cold signal via AHP2 (Arabidopsis histidine kinase 2), AHP3, or AHP5.
      Title: Arabidopsis response Regulator1 and Arabidopsis histidine phosphotransfer Protein2 (AHP2), AHP3, and AHP5 function in cold signaling.
    3. Arabidopsis AHP2, AHP3, and AHP5 histidine phosphotransfer proteins function as redundant negative regulators of drought stress response.
      Title: Arabidopsis AHP2, AHP3, and AHP5 histidine phosphotransfer proteins function as redundant negative regulators of drought stress response.
    Submit: New GeneRIF Correction

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    NM_001344287.1

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables histidine phosphotransfer kinase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein histidine kinase binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within antipodal cell differentiation IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within cytokinin-activated signaling pathway IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within embryo sac egg cell differentiation IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within phosphorelay signal transduction system ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    acts_upstream_of_or_within phosphorylation IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of cytokinin-activated signaling pathway IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within signal transduction IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm HDA PubMed 
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus HDA PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plastid HDA PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    histidine-containing phosphotransmitter 3
    NP_001318703.1
    • histidine-containing phosphotransmitter 3 (AHP3); CONTAINS InterPro DOMAIN/s: Signal transduction histidine kinase, phosphotransfer (Hpt) domain (InterPro:IPR008207); BEST Arabidopsis thaliana protein match is: histidine-containing phosphotransmitter 2 (TAIR:AT3G29350.1); Has 358 Blast hits to 357 proteins in 69 species: Archae - 2; Bacteria - 65; Metazoa - 0; Fungi - 23; Plants - 266; Viruses - 0; Other Eukaryotes - 2 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      15748731..15750891
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001344288.1 → NP_001330682.1  histidine-containing phosphotransmitter 3 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8BBL2
      Conserved Domains (1) summary
      pfam01627
      Location:95 → 180
      Hpt; Hpt domain

    2. NM_001344289.1 → NP_001330681.1  histidine-containing phosphotransmitter 3 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8BBL2
      Conserved Domains (1) summary
      pfam01627
      Location:95 → 180
      Hpt; Hpt domain

    3. NM_123296.4 → NP_198750.2  histidine-containing phosphotransmitter 3 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8BBL0

    4. NM_001344287.1 → NP_001318703.1  histidine-containing phosphotransmitter 3 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9SAZ5, Q9ZWM4
      UniProtKB/TrEMBL
      A0A178URE5, A0A5S9Y9T9
      Conserved Domains (1) summary
      pfam01627
      Location:46 → 131
      Hpt; Hpt domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9SAZ5.2

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.