FTSZ1-1 homolog of bacterial cytokinesis Z-ring protein FTSZ 1-1 [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Official Symbol: FTSZ1-1
Official Full Name: homolog of bacterial cytokinesis Z-ring protein FTSZ 1-1
Primary source: TAIR:AT5G55280
Locus tag: AT5G55280
See related: Araport:AT5G55280
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: ARABIDOPSIS THALIANA HOMOLOG OF BACTERIAL CYTOKINESIS Z-RING PROTEIN FTSZ 1-1; ATFTSZ1-1; CHLOROPLAST FTSZ; CPFTSZ; homolog of bacterial cytokinesis Z-ring protein FTSZ 1-1; MCO15.23; MCO15_23
Summary: Encodes one of two FtsZ proteins, tubulin-like proteins, in Arabidopsis. It is involved in chloroplast division.
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Genomic context

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See FTSZ1-1 in Genome Data Viewer

Location:: chromosome: 5

Exon count:: 6

Sequence:: Chromosome: 5; NC_003076.8 (22420600..22422649, complement)

Chromosome 5 - NC_003076.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003076.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

A novel amphiphilic motif at the C-terminus of FtsZ1 facilitates chloroplast division.
Title: A novel amphiphilic motif at the C-terminus of FtsZ1 facilitates chloroplast division.
FtsZ1 and FtsZ2 can heteropolymerize into a contractible ring ex vivo. Fluorescently labelled FtsZ1 and/or FtsZ2 formed single rings in cells of the yeast Pichia pastoris. Photobleaching experiments indicated that co-assembly of FtsZ1 and FtsZ2 imparts polarity to polymerization.
Title: Chloroplast FtsZ assembles into a contractible ring via tubulin-like heteropolymerization.
In plants lacking ARC3, the key negative regulator of FtsZ assembly, FtsZ1/FtsZ2 turnover was threefold slower.
Title: FtsZ1/FtsZ2 Turnover in Chloroplasts and the Role of ARC3.
These results suggest that besides ARC6-mediated anchoring, an additional FtsZ-anchoring mechanism is present in chloroplasts.
Title: Single particle tracking analysis of the chloroplast division protein FtsZ anchoring to the inner envelope membrane.
FtsZ1 and FtsZ2-1 are capable of in vitro self-assembly into two distinct filament types, termed type-I and type-II. During assembly of the type-II filaments the most common intermediate between the dimer and filament state is a tetramer.
Title: Oligomerization of plant FtsZ1 and FtsZ2 plastid division proteins.
Plastids in pollen grains and growing tubes from transgenic Arabidopsis thaliana lines expressing stroma-localised FtsZ1-green-fluorescent protein fusion in a vegetative cell-specific manner, are presented.
Title: Dynamic morphologies of pollen plastids visualised by vegetative-specific FtsZ1-GFP in Arabidopsis thaliana.
Evolution of FtsZ-1 in green plants, perhaps arising from an enhanced capacity for the regulation of Z ring composition and activity in vivo.
Title: GTP-dependent heteropolymer formation and bundling of chloroplast FtsZ1 and FtsZ2.
Specific GTPase activities were determined and found to be different for FtsZ1-1 vs. FtsZ2-1.
Title: Plant FtsZ1 and FtsZ2 expressed in a eukaryotic host: GTPase activity and self-assembly.
Results describe the in vivo quantitative relationship between plastid division proteins FtsZ1 and FtsZ2 and identification of ARC6 and ARC3 in a native FtsZ complex.
Title: In vivo quantitative relationship between plastid division proteins FtsZ1 and FtsZ2 and identification of ARC6 and ARC3 in a native FtsZ complex.
The chloroplast division site placement involves a balance between the opposing activities of AtMinE1 and AtMinD1, which acts to prevent FtsZ ring formation anywhere outside of the mid-chloroplast.
Title: The assembly of the FtsZ ring at the mid-chloroplast division site depends on a balance between the activities of AtMinE1 and ARC11/AtMinD1.

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Homology

Orthologs from OrthoDB

NM_124910.6

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables GTPase activity	IDA Inferred from Direct Assay more info	PubMed
enables identical protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
acts_upstream_of_or_within chloroplast fission	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in chloroplast organization	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in chloroplast relocation	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in microtubule-based process	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within plastid fission	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in response to blue light	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in chloroplast	HDA more info	PubMed
located_in chloroplast	ISM Inferred from Sequence Model more info
located_in chloroplast stroma	HDA more info	PubMed
located_in chloroplast stroma	IDA Inferred from Direct Assay more info	PubMed
colocalizes_with chloroplast thylakoid membrane	IDA Inferred from Direct Assay more info	PubMed
located_in contractile ring	IDA Inferred from Direct Assay more info	PubMed
located_in microtubule	IEA Inferred from Electronic Annotation more info
located_in plastid	HDA more info	PubMed

General protein information

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Preferred Names: homolog of bacterial cytokinesis Z-ring protein FTSZ 1-1

NP_200339.1

homolog of bacterial cytokinesis Z-ring protein FTSZ 1-1 (FTSZ1-1); FUNCTIONS IN: protein binding, structural molecule activity; INVOLVED IN: chloroplast fission, plastid fission; LOCATED IN: chloroplast stroma, chloroplast; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Cell division protein FtsZ, N-terminal (InterPro:IPR000158), Tubulin, conserved site (InterPro:IPR017975), Cell division protein FtsZ, conserved site (InterPro:IPR020805), Tubulin/FtsZ, GTPase domain (InterPro:IPR003008), Tubulin/FtsZ, N-terminal (InterPro:IPR019746), Tubulin/FtsZ, C-terminal (InterPro:IPR008280), Tubulin/FtsZ, 2-layer sandwich domain (InterPro:IPR018316); BEST Arabidopsis thaliana protein match is: Tubulin/FtsZ family protein (TAIR:AT3G52750.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003076.8 Reference assembly

Range

22420600..22422649 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_124910.6 → NP_200339.1 homolog of bacterial cytokinesis Z-ring protein FTSZ 1-1 [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_200339.1

Status: REVIEWED

UniProtKB/Swiss-Prot

Q42545, Q9FLN6

UniProtKB/TrEMBL

A0A178U8G2, A0A5S9YGJ0

Conserved Domains (1) summary

PRK09330
Location:91 → 433

PRK09330; cell division protein FtsZ; Validated