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    NAS2 nicotianamine synthase 2 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 835707, updated on 18-Sep-2024

    Summary

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    Official Symbol
    NAS2
    Official Full Name
    nicotianamine synthase 2
    Primary source
    TAIR:AT5G56080
    Locus tag
    AT5G56080
    See related
    Araport:AT5G56080
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ARABIDOPSIS THALIANA NICOTIANAMINE SYNTHASE 2; ATNAS2; MDA7.14; MDA7_14; nicotianamine synthase 2
    Summary
    Encodes a protein with nicotianamine synthase activity. Its transcript levels rise in roots in response to zinc deficiency and rise in leaves in response to elevated levels of zinc.
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    Genomic context

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    See NAS2 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    1
    Sequence:
    Chromosome: 5; NC_003076.8 (22711141..22712441, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene methyltransferase small domain protein, putative (DUF2431) Neighboring gene cytochrome c oxidase 15 Neighboring gene glycine-rich protein / oleosin Neighboring gene myb domain protein 103

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Nicotianamine functions in the Phloem-based transport of iron to sink organs, in pollen development and pollen tube growth in Arabidopsis. Schuler M, et al. Plant Cell, 2012 Jun. PMID 22706286, Free PMC Article
    2. Comparative microarray analysis of Arabidopsis thaliana and Arabidopsis halleri roots identifies nicotianamine synthase, a ZIP transporter and other genes as potential metal hyperaccumulation factors. Weber M, et al. Plant J, 2004 Jan. PMID 14690510
    3. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables nicotianamine synthase activity IDA
    Inferred from Direct Assay
    more info
    		  
    enables nicotianamine synthase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within nicotianamine biosynthetic process IDA
    Inferred from Direct Assay
    more info
    		  
    involved_in nicotianamine biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within phloem transport IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within pollen development IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within pollen tube growth IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within response to zinc ion IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    nicotianamine synthase 2
    NP_200419.1
    • nicotianamine synthase 2 (NAS2); CONTAINS InterPro DOMAIN/s: Nicotianamine synthase (InterPro:IPR004298); BEST Arabidopsis thaliana protein match is: nicotianamine synthase 1 (TAIR:AT5G04950.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      22711141..22712441 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_124990.2 → NP_200419.1  nicotianamine synthase 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_200419.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A2RVM2, Q9FKT9, Q9ZWF7
      UniProtKB/TrEMBL
      A0A178ULG9, A0A5S9YF51, A0A654GBE8
      Conserved Domains (1) summary
      PLN03075
      Location:1 → 296
      PLN03075; nicotianamine synthase; Provisional
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9FKT9.1

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