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    OXA1 inner membrane OXA1-like protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 836325, updated on 18-Sep-2024

    Summary

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    Official Symbol
    OXA1
    Official Full Name
    inner membrane OXA1-like protein
    Primary source
    TAIR:AT5G62050
    Locus tag
    AT5G62050
    See related
    Araport:AT5G62050
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ARABIDOPSIS THALIANA HOMOLOG OF YEAST OXIDASE ASSEMBLY 1 (OXA1); ATOXA1; homolog of yeast oxidase assembly 1 (OXA1); HOMOLOG OF YEAST OXIDASE ASSEMBLY 1 (OXA1) IN ARABIDOPSIS THALIANA; MTG10.19; MTG10_19; OXA1AT
    Summary
    essential factor for protein sorting and assembly into membranes
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    Genomic context

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    See OXA1 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    10
    Sequence:
    Chromosome: 5; NC_003076.8 (24923465..24927314, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene heat shock transcription factor B2A Neighboring gene diphthamide synthesis DPH2 family protein Neighboring gene PEBP (phosphatidylethanolamine-binding protein) family protein Neighboring gene F-box and associated interaction domains-containing protein Neighboring gene Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Arabidopsis thaliana Oxa proteins locate to mitochondria and fulfill essential roles during embryo development. Benz M, et al. Planta, 2013 Feb. PMID 23179441
    2. Functional complementation of an oxa1- yeast mutation identifies an Arabidopsis thaliana cDNA involved in the assembly of respiratory complexes. Hamel P, et al. Plant J, 1997 Dec. PMID 9450344
    3. Mitochondrial localization of AtOXA1, an arabidopsis homologue of yeast Oxa1p involved in the insertion and assembly of protein complexes in mitochondrial inner membrane. Sakamoto W, et al. Plant Cell Physiol, 2000 Oct. PMID 11148275
    4. Chloroplast Oxa1p homolog albino3 is required for post-translational integration of the light harvesting chlorophyll-binding protein into thylakoid membranes. Moore M, et al. J Biol Chem, 2000 Jan 21. PMID 10636840
    5. A transcriptomic and proteomic characterization of the Arabidopsis mitochondrial protein import apparatus and its response to mitochondrial dysfunction. Lister R, et al. Plant Physiol, 2004 Feb. PMID 14730085, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Oxa1a and Oxa2 proteins function in embryo formation although at different developmental stages.
      Title: Arabidopsis thaliana Oxa proteins locate to mitochondria and fulfill essential roles during embryo development.
    Submit: New GeneRIF Correction

    General gene information

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    NM_125598.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables membrane insertase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein-transporting ATPase activity IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within protein insertion into mitochondrial inner membrane TAS
    Traceable Author Statement
    more info
    		 PubMed 
    acts_upstream_of_or_within protein-containing complex assembly IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in mitochondrial inner membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in mitochondrion HDA PubMed 
    located_in mitochondrion IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    inner membrane OXA1-like protein
    NP_201011.1
    • homolog of yeast oxidase assembly 1 (OXA1) (OXA1); FUNCTIONS IN: P-P-bond-hydrolysis-driven protein transmembrane transporter activity; INVOLVED IN: protein import into mitochondrial inner membrane, protein complex assembly; LOCATED IN: mitochondrion, mitochondrial inner membrane; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Membrane insertion protein, OxaA/YidC (InterPro:IPR001708), Membrane insertion protein, OxaA/YidC, core (InterPro:IPR020001); BEST Arabidopsis thaliana protein match is: inner membrane protein OXA1-like (TAIR:AT2G46470.1); Has 6982 Blast hits to 6979 proteins in 2374 species: Archae - 0; Bacteria - 4991; Metazoa - 235; Fungi - 246; Plants - 190; Viruses - 0; Other Eukaryotes - 1320 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      24923465..24927314 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_125598.4 → NP_201011.1  inner membrane OXA1-like protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_201011.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q42190, Q42191
      UniProtKB/TrEMBL
      A0A178UA29, A0A5S9YGS0
      Conserved Domains (1) summary
      cd19751
      Location:153 → 345
      5TM_YidC_Oxa1_Alb3; Five transmembrane core domain of YidC/Oxa1/Alb3 protein family of insertases
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q42191.2

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