MK mevalonate kinase [Arabidopsis thaliana (thale cress)] - Gene

Summary

Official Symbol: MK
Official Full Name: mevalonate kinase
Primary source: TAIR:AT5G27450
Locus tag: AT5G27450
See related: Araport:AT5G27450
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: F21A20.160; F21A20_160; mevalonate kinase; MEVALONATE KINASE; MVK
Summary: Encodes a protein with mevalonate kinase activity involved in the mevalonate pathway.
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Chromosome 5 - NC_003076.8 Genomic Context describing neighboring genes

Go to nucleotide: Graphics FASTA GenBank

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NM_001203482.1

NM_122627.6

NM_180753.4

Function	Evidence Code	Pubs
enables ATP binding	ISS Inferred from Sequence or Structural Similarity more info
enables magnesium ion binding	ISS Inferred from Sequence or Structural Similarity more info
enables mevalonate kinase activity	IGI Inferred from Genetic Interaction more info	PubMed
enables mevalonate kinase activity	ISS Inferred from Sequence or Structural Similarity more info

Process	Evidence Code	Pubs
involved_in isopentenyl diphosphate biosynthetic process, mevalonate pathway	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within phosphorylation	IGI Inferred from Genetic Interaction more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	IDA Inferred from Direct Assay more info	PubMed
located_in cytosol	HDA more info	PubMed

NP_001190411.1

mevalonate kinase (MK); FUNCTIONS IN: mevalonate kinase activity; INVOLVED IN: isoprenoid biosynthetic process, metabolic process, phosphorylation; LOCATED IN: cytoplasm; EXPRESSED IN: 30 plant structures; EXPRESSED DURING: 16 growth stages; CONTAINS InterPro DOMAIN/s: Mevalonate kinase (InterPro:IPR006205), GHMP kinase, ATP-binding, conserved site (InterPro:IPR006203), Mevalonate/galactokinase (InterPro:IPR006206), Ribosomal protein S5 domain 2-type fold (InterPro:IPR020568), GHMP kinase (InterPro:IPR006204), Ribosomal protein S5 domain 2-type fold, subgroup (InterPro:IPR014721), GHMP kinase, C-terminal (InterPro:IPR013750).

NP_198097.1

mevalonate kinase (MK); FUNCTIONS IN: mevalonate kinase activity; INVOLVED IN: isoprenoid biosynthetic process, metabolic process, phosphorylation; LOCATED IN: cytoplasm; EXPRESSED IN: 30 plant structures; EXPRESSED DURING: 16 growth stages; CONTAINS InterPro DOMAIN/s: Mevalonate kinase (InterPro:IPR006205), GHMP kinase, ATP-binding, conserved site (InterPro:IPR006203), Mevalonate/galactokinase (InterPro:IPR006206), Ribosomal protein S5 domain 2-type fold (InterPro:IPR020568), GHMP kinase (InterPro:IPR006204), Ribosomal protein S5 domain 2-type fold, subgroup (InterPro:IPR014721), GHMP kinase, C-terminal (InterPro:IPR013750); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

NP_851084.1

mevalonate kinase (MK); FUNCTIONS IN: mevalonate kinase activity; INVOLVED IN: isoprenoid biosynthetic process, metabolic process, phosphorylation; LOCATED IN: cytoplasm; EXPRESSED IN: 30 plant structures; EXPRESSED DURING: 16 growth stages; CONTAINS InterPro DOMAIN/s: Mevalonate kinase (InterPro:IPR006205), GHMP kinase, ATP-binding, conserved site (InterPro:IPR006203), Mevalonate/galactokinase (InterPro:IPR006206), Ribosomal protein S5 domain 2-type fold (InterPro:IPR020568), GHMP kinase (InterPro:IPR006204), Ribosomal protein S5 domain 2-type fold, subgroup (InterPro:IPR014721), GHMP kinase, C-terminal (InterPro:IPR013750); Has 2155 Blast hits to 2126 proteins in 899 species: Archae - 214; Bacteria - 1320; Metazoa - 166; Fungi - 147; Plants - 62; Viruses - 0; Other Eukaryotes - 246 (source: NCBI BLink).