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    UGLYAH ureidoglycine aminohydrolase [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 827413, updated on 18-Sep-2024

    Summary

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    Official Symbol
    UGLYAH
    Official Full Name
    ureidoglycine aminohydrolase
    Primary source
    TAIR:AT4G17050
    Locus tag
    AT4G17050
    See related
    Araport:AT4G17050
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    DL4555W; FCAALL.343; ureidoglycine aminohydrolase
    Summary
    Encodes a protein with ureidoglycine aminohydrolase activity.
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    Genomic context

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    See UGLYAH in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    13
    Sequence:
    Chromosome: 4; NC_003075.7 (9589501..9592590)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene expansin-like B1 Neighboring gene CLP protease R subunit 4 Neighboring gene FRIGIDA interacting protein 2 Neighboring gene peptidyl-prolyl cis-trans isomerase Neighboring gene Histone H3 K4-specific methyltransferase SET7/9 family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003075.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The ureide-degrading reactions of purine ring catabolism employ three amidohydrolases and one aminohydrolase in Arabidopsis, soybean, and rice. Werner AK, et al. Plant Physiol, 2013 Oct. PMID 23940254, Free PMC Article
    2. Ureide catabolism in Arabidopsis thaliana and Escherichia coli. Werner AK, et al. Nat Chem Biol, 2010 Jan. PMID 19935661
    3. Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes. Riechmann JL, et al. Science, 2000 Dec 15. PMID 11118137
    4. Global Analysis of Membrane-associated Protein Oligomerization Using Protein Correlation Profiling. McBride Z, et al. Mol Cell Proteomics, 2017 Nov. PMID 28887381, Free PMC Article
    5. Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana. Mayer K, et al. Nature, 1999 Dec 16. PMID 10617198

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    NM_117809.6

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables ureidoglycine aminohydrolase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within allantoin catabolic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within purine nucleobase catabolic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within purine nucleobase catabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of DNA-templated transcription TAS
    Traceable Author Statement
    more info
    		 PubMed 
    acts_upstream_of_or_within ureide catabolic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within ureide catabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol HDA PubMed 

    General protein information

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    Preferred Names
    ureidoglycine aminohydrolase
    NP_193438.2
    • ureidoglycine aminohydrolase (UGLYAH); FUNCTIONS IN: ureidoglycine aminohydrolase activity, sequence-specific DNA binding transcription factor activity; INVOLVED IN: allantoin catabolic process, regulation of transcription; LOCATED IN: endomembrane system; CONTAINS InterPro DOMAIN/s: Cupin 2, conserved barrel (InterPro:IPR013096), Cupin, RmlC-type (InterPro:IPR011051), RmlC-like jelly roll fold (InterPro:IPR014710); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      9589501..9592590
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_117809.6 → NP_193438.2  ureidoglycine aminohydrolase [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_193438.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O23549, Q67XN1, Q680J5, Q8GXV5
      UniProtKB/TrEMBL
      A0A178V1S3, A0A654FQ37
      Conserved Domains (1) summary
      PRK11171
      Location:55 → 298
      PRK11171; (S)-ureidoglycine aminohydrolase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8GXV5.1

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