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    NTT1 nucleotide transporter 1 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 844370, updated on 18-Sep-2024

    Summary

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    Official Symbol
    NTT1
    Official Full Name
    nucleotide transporter 1
    Primary source
    TAIR:AT1G80300
    Locus tag
    AT1G80300
    See related
    Araport:AT1G80300
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    AATP1; ATNTT1; F5I6.5; F5I6_5; nucleotide transporter 1
    Summary
    Encodes an ATP/ADP transporter.
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    Genomic context

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    See NTT1 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    5
    Sequence:
    Chromosome: 1; NC_003070.9 (30191538..30194605)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene PENTATRICOPEPTIDE REPEAT 596 Neighboring gene alpha/beta-Hydrolases superfamily protein Neighboring gene Nucleotide-diphospho-sugar transferases superfamily protein Neighboring gene ncRNA Neighboring gene uncharacterized protein Neighboring gene sulfate transmembrane transporter Neighboring gene 2-oxoglutarate (2OG) and Fe(II)-dependent oxygenase superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Oligomeric status and nucleotide binding properties of the plastid ATP/ADP transporter 1: toward a molecular understanding of the transport mechanism. Deniaud A, et al. PLoS One, 2012. PMID 22438876, Free PMC Article
    2. Expression of a chloroplast ATP/ADP transporter in E. coli membranes: behind the Mistic strategy. Deniaud A, et al. Biochim Biophys Acta, 2011 Aug. PMID 21550334
    3. VH1/BRL2 receptor-like kinase interacts with vascular-specific adaptor proteins VIT and VIK to influence leaf venation. Ceserani T, et al. Plant J, 2009 Mar. PMID 19000166, Free PMC Article
    4. Proteomic study of the Arabidopsis thaliana chloroplastic envelope membrane utilizing alternatives to traditional two-dimensional electrophoresis. Froehlich JE, et al. J Proteome Res, 2003 Jul-Aug. PMID 12938931
    5. AT_CHLORO, a comprehensive chloroplast proteome database with subplastidial localization and curated information on envelope proteins. Ferro M, et al. Mol Cell Proteomics, 2010 Jun. PMID 20061580, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Nucleotide binding studies and analysis of NTT1 mutants lead us to suggest the existence of two distinct and probably inter-dependent binding sites.
      Title: Oligomeric status and nucleotide binding properties of the plastid ATP/ADP transporter 1: toward a molecular understanding of the transport mechanism.
    2. Report Mistic fusion approach is a valuable strategy for obtaining quantities of pure/active NTT1 adequate for structural studies.
      Title: Expression of a chloroplast ATP/ADP transporter in E. coli membranes: behind the Mistic strategy.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_106679.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables ATP:ADP antiporter activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables ATP:ADP antiporter activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in chloroplast envelope HDA PubMed 
    located_in mitochondrion HDA PubMed 
    located_in plastid HDA PubMed 

    General protein information

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    Preferred Names
    nucleotide transporter 1
    NP_178146.1
    • nucleotide transporter 1 (NTT1); FUNCTIONS IN: ATP:ADP antiporter activity; INVOLVED IN: transport; LOCATED IN: membrane, chloroplast envelope; EXPRESSED IN: stem, root, guard cell, callus, leaf; EXPRESSED DURING: seedling growth; CONTAINS InterPro DOMAIN/s: ADP/ATP carrier protein (InterPro:IPR004667); BEST Arabidopsis thaliana protein match is: TLC ATP/ADP transporter (TAIR:AT1G15500.1); Has 784 Blast hits to 777 proteins in 180 species: Archae - 0; Bacteria - 480; Metazoa - 8; Fungi - 28; Plants - 103; Viruses - 0; Other Eukaryotes - 165 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      30191538..30194605
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_106679.3 → NP_178146.1  nucleotide transporter 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_178146.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q39002, Q94AN9, Q9C974
      UniProtKB/TrEMBL
      A0A178W3C1, A0A5S9WW08, A0A654ES94, Q0WW68
      Conserved Domains (1) summary
      TIGR00769
      Location:108 → 574
      AAA; ADP/ATP carrier protein family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q39002.2

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