gngt2a guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2a [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: gngt2aprovided by ZNC
Official Full Name: guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2aprovided by ZNC
Primary source: ZFIN:ZDB-GENE-030131-7595
See related: Ensembl:ENSDARG00000010680 AllianceGenome:ZFIN:ZDB-GENE-030131-7595
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: gngt2; id:ibd1139; wu:fk53d05
Summary: Predicted to enable G-protein beta-subunit binding activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to act upstream of or within signal transduction. Predicted to be located in plasma membrane. Predicted to be part of heterotrimeric G-protein complex. Is expressed in myotome; pineal complex; visual system; and yolk syncytial layer. Orthologous to human GNGT2 (G protein subunit gamma transducin 2). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 3

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	3	NC_007114.7 (23092760..23096135)
105	previous assembly	GRCz10 (GCF_000002035.5)	3	NC_007114.6 (22962212..22965587)

Chromosome 3 - NC_007114.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables G-protein beta-subunit binding	IBA Inferred from Biological aspect of Ancestor more info
enables G-protein beta-subunit binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in G protein-coupled receptor signaling pathway	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within G protein-coupled receptor signaling pathway	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within signal transduction	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
part_of heterotrimeric G-protein complex	IBA Inferred from Biological aspect of Ancestor more info
part_of heterotrimeric G-protein complex	IEA Inferred from Electronic Annotation more info
located_in membrane	IEA Inferred from Electronic Annotation more info
located_in plasma membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2a

Names: guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2; transducin gamma (cone)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001302500.1 → NP_001289429.1 guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2a

See identical proteins and their annotated locations for NP_001289429.1

Status: VALIDATED

Description

Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein.

Source sequence(s)

CT573473, EH451823, EH455226, EH456883

UniProtKB/TrEMBL

A0A8M1P740, Q6PBR4

Related

ENSDARP00000014423.6, ENSDART00000024136.7

Conserved Domains (1) summary

smart00224
Location:8 → 69

GGL; G protein gamma subunit-like motifs
NM_001302501.1 → NP_001289430.1 guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2a

See identical proteins and their annotated locations for NP_001289430.1

Status: VALIDATED

Description

Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Both variants 1 and 2 encode the same protein.

Source sequence(s)

CT573473, EH451823, EH456883

UniProtKB/TrEMBL

A0A8M1P740, Q6PBR4

Related

ENSDARP00000117694.1, ENSDART00000142884.2

Conserved Domains (1) summary

smart00224
Location:8 → 69

GGL; G protein gamma subunit-like motifs