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    cycsb cytochrome c, somatic b [ Danio rerio (zebrafish) ]

    Gene ID: 415158, updated on 4-Jan-2025

    Summary

    Official Symbol
    cycsbprovided by ZNC
    Official Full Name
    cytochrome c, somatic bprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040625-38
    See related
    Ensembl:ENSDARG00000044562 AllianceGenome:ZFIN:ZDB-GENE-040625-38
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    cyc; fk52b01; zgc:86706; wu:fk52b01
    Summary
    Predicted to enable electron transfer activity. Predicted to be involved in mitochondrial electron transport, cytochrome c to oxygen and mitochondrial electron transport, ubiquinol to cytochrome c. Predicted to be located in mitochondrion. Predicted to be active in mitochondrial intermembrane space. Human ortholog(s) of this gene implicated in cholangiocarcinoma; lung non-small cell carcinoma; pancreatic cancer; and thrombocytopenia. Orthologous to human CYCS (cytochrome c, somatic). [provided by Alliance of Genome Resources, Jan 2025]
    Orthologs
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    Genomic context

    See cycsb in Genome Data Viewer
    Location:
    chromosome: 6
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 6 NC_007117.7 (10910676..10912355, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 6 NC_007117.6 (10675249..10676928, complement)

    Chromosome 6 - NC_007117.7Genomic Context describing neighboring genes Neighboring gene metaxin 2 Neighboring gene nfe2 like bZIP transcription factor 2b Neighboring gene chemokine (C-C motif) receptor 7 Neighboring gene notum pectinacetylesterase 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Pathways from PubChem

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables electron transfer activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables electron transfer activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables heme binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in mitochondrial electron transport, cytochrome c to oxygen IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in mitochondrial electron transport, ubiquinol to cytochrome c IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in mitochondrial intermembrane space IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
     

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001002068.1NP_001002068.1  cytochrome c

      See identical proteins and their annotated locations for NP_001002068.1

      Status: PROVISIONAL

      Source sequence(s)
      BC071383
      UniProtKB/Swiss-Prot
      Q6IQM2
      Related
      ENSDARP00000034555.5, ENSDART00000036456.6
      Conserved Domains (1) summary
      COG3474
      Location:1104
      Cyc7; Cytochrome c2 [Energy production and conversion]

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007117.7 Reference GRCz11 Primary Assembly

      Range
      10910676..10912355 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)