larp6b La ribonucleoprotein 6, translational regulator b [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: larp6bprovided by ZNC
Official Full Name: La ribonucleoprotein 6, translational regulator bprovided by ZNC
Primary source: ZFIN:ZDB-GENE-041008-244
See related: Ensembl:ENSDARG00000003968 AllianceGenome:ZFIN:ZDB-GENE-041008-244
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: im:7142825; wu:fa55b04; zgc:162969
Summary: Predicted to enable mRNA binding activity. Predicted to act upstream of or within RNA processing. Predicted to be part of ribonucleoprotein complex. Predicted to be active in nucleus. Orthologous to human LARP6 (La ribonucleoprotein 6, translational regulator). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Genomic context

Location:: chromosome: 11

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	11	NC_007122.7 (6446235..6452467, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	11	NC_007122.6 (6436396..6442628, complement)

Chromosome 11 - NC_007122.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Larp6 proteins are required for normal oocyte development, chorion formation and egg activation
Title: Maternal Larp6 controls oocyte development, chorion formation and elevation.

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables RNA binding	IEA Inferred from Electronic Annotation more info
enables mRNA binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within RNA processing	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleus	IEA Inferred from Electronic Annotation more info
part_of ribonucleoprotein complex	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: la-related protein 6b

Names: La ribonucleoprotein domain family, member 6; La ribonucleoprotein domain family, member 6b

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001089408.1 → NP_001082877.1 la-related protein 6b

See identical proteins and their annotated locations for NP_001082877.1

Status: PROVISIONAL

Source sequence(s)

BC134173

UniProtKB/TrEMBL

A3KP60

Related

ENSDARP00000019822.6, ENSDART00000004483.8

Conserved Domains (3) summary

cd08033
Location:62 → 138

LARP_6; La RNA-binding domain of La-related protein 6

pfam12901
Location:445 → 459

SUZ-C; SUZ-C motif

cl17169
Location:153 → 261

RRM_SF; RNA recognition motif (RRM) superfamily