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    ecrg4a ECRG4 augurin precursor a [ Danio rerio (zebrafish) ]

    Gene ID: 791762, updated on 9-Dec-2024

    Summary

    Official Symbol
    ecrg4aprovided by ZNC
    Official Full Name
    ECRG4 augurin precursor aprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-050417-189
    See related
    Ensembl:ENSDARG00000056087 AllianceGenome:ZFIN:ZDB-GENE-050417-189
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:112443
    Summary
    Acts upstream of or within central nervous system development and regulation of cell population proliferation. Predicted to be located in apical plasma membrane and cytoplasm. Predicted to be active in extracellular space. Is expressed in epidermis; pectoral fin; and pharyngeal arch. Orthologous to human ECRG4 (ECRG4 augurin precursor). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See ecrg4a in Genome Data Viewer
    Location:
    chromosome: 9
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 9 NC_007120.7 (6371919..6380653, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 9 NC_007120.6 (6393934..6402668, complement)

    Chromosome 9 - NC_007120.7Genomic Context describing neighboring genes Neighboring gene ST6 beta-galactosamide alpha-2,6-sialyltranferase 2a Neighboring gene teleost multiple tissue opsin 2b Neighboring gene UDP-glucuronate decarboxylase 1 Neighboring gene NCK adaptor protein 2a Neighboring gene uncharacterized LOC137496441

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Clone Names

    • MGC112443

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in G1 to G0 transition IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in anaphase-promoting complex-dependent catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in cellular senescence IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in central nervous system development IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within central nervous system development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in negative regulation of cell population proliferation ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    involved_in regulation of cell population proliferation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within regulation of cell population proliferation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in response to wounding ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in apical plasma membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytoplasm ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in extracellular space IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in extracellular space ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    augurin-A
    Names
    esophageal cancer related gene 4a
    esophageal cancer-related gene 4
    esophageal cancer-related gene 4-A protein homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001017697.1NP_001017697.1  augurin-A precursor

      See identical proteins and their annotated locations for NP_001017697.1

      Status: PROVISIONAL

      Source sequence(s)
      BC093311
      UniProtKB/Swiss-Prot
      F1R4S5, Q566V9
      Related
      ENSDARP00000072984.3, ENSDART00000078523.5
      Conserved Domains (1) summary
      pfam15187
      Location:29142
      Augurin; Oesophageal cancer-related gene 4

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007120.7 Reference GRCz11 Primary Assembly

      Range
      6371919..6380653 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)