U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    gtpbp1 GTP binding protein 1 [ Danio rerio (zebrafish) ]

    Gene ID: 378721, updated on 27-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    gtpbp1provided by ZNC
    Official Full Name
    GTP binding protein 1provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030909-12
    See related
    Ensembl:ENSDARG00000053467 AllianceGenome:ZFIN:ZDB-GENE-030909-12
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    cb858; zgc:66228; wu:fb36e06; wu:fi39g05
    Summary
    Predicted to enable GTP binding activity and GTPase activity. Is expressed in intermediate cell mass of mesoderm; intermediate mesoderm; lens; solid lens vesicle; and ventral mesoderm. Orthologous to human GTPBP1 (GTP binding protein 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See gtpbp1 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 3 NC_007114.7 (33440641..33459767)
    105 previous assembly GRCz10 (GCF_000002035.5) 3 NC_007114.6 (33308834..33328050)

    Chromosome 3 - NC_007114.7Genomic Context describing neighboring genes Neighboring gene si:dkey-283b1.7 Neighboring gene ribosomal protein L23 Neighboring gene small G protein signaling modulator 3 Neighboring gene protein phosphatase 1 regulatory subunit 29

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Expression

    Go to the top of the page Help
    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. GTP-Binding Protein 1-Like (GTPBP1l) Regulates Vascular Patterning during Zebrafish Development. Lo YH, et al. Biomedicines, 2022 Dec 10. PMID 36551964, Free PMC Article
    2. A permissive epigenetic landscape facilitates distinct transcriptional signatures of activating transcription factor 6 in the liver. Ramdas Nair A, et al. Genomics, 2022 Jan. PMID 34863900
    3. XBP-1, a key regulator of unfolded protein response, activates transcription of IGF1 and Akt phosphorylation in zebrafish embryonic cell line. Hu MC, et al. Biochem Biophys Res Commun, 2007 Aug 3. PMID 17560942
    4. Loss of gata1 but not gata2 converts erythropoiesis to myelopoiesis in zebrafish embryos. Galloway JL, et al. Dev Cell, 2005 Jan. PMID 15621534
    5. Spatio-temporal regulation of Wnt and retinoic acid signaling by tbx16/spadetail during zebrafish mesoderm differentiation. Mueller RL, et al. BMC Genomics, 2010 Sep 9. PMID 20828405, Free PMC Article

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables GTP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    GTP-binding protein 1

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_213475.1 → NP_998640.2  GTP-binding protein 1

      Status: PROVISIONAL

      Source sequence(s)
      BC057488
      UniProtKB/TrEMBL
      A0A8N1TRQ8, Q6PFN0
      Related
      ENSDARP00000113119.1, ENSDART00000146005.3
      Conserved Domains (4) summary
      cd04165
      Location:161 → 385
      GTPBP1_like; GTP binding protein 1 (GTPBP1)-like family includes GTPBP2
      COG5258
      Location:77 → 573
      GTPBP1; GTPase [General function prediction only]
      cd03694
      Location:394 → 480
      GTPBP_II; Domain II of the GTPBP family of GTP binding proteins
      cd03708
      Location:486 → 572
      GTPBP_III; Domain III of the GP-1 family of GTPases

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007114.7 Reference GRCz11 Primary Assembly

      Range
      33440641..33459767
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005163999.5 → XP_005164056.1  GTP-binding protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A8M2BBB3, Q6PFN0
      Conserved Domains (4) summary
      cd04165
      Location:161 → 385
      GTPBP1_like; GTP binding protein 1 (GTPBP1)-like family includes GTPBP2
      COG5258
      Location:77 → 573
      GTPBP1; GTPase [General function prediction only]
      cd03694
      Location:394 → 480
      GTPBP_II; Domain II of the GTPBP family of GTP binding proteins
      cd03708
      Location:486 → 572
      GTPBP_III; Domain III of the GP-1 family of GTPases

    2. XM_005164001.5 → XP_005164058.1  GTP-binding protein 1 isoform X2

      UniProtKB/TrEMBL
      A0A8M2BB58, Q6PFN0
      Conserved Domains (4) summary
      cd04165
      Location:161 → 385
      GTPBP1_like; GTP binding protein 1 (GTPBP1)-like family includes GTPBP2
      COG5258
      Location:77 → 571
      GTPBP1; GTPase [General function prediction only]
      cd03694
      Location:394 → 480
      GTPBP_II; Domain II of the GTPBP family of GTP binding proteins
      cd03708
      Location:486 → 571
      GTPBP_III; Domain III of the GP-1 family of GTPases

    3. XM_021469768.2 → XP_021325443.1  GTP-binding protein 1 isoform X3

      UniProtKB/TrEMBL
      A0A8M9PEZ2, Q6PFN0
      Conserved Domains (2) summary
      cd04165
      Location:161 → 385
      GTPBP1_like; GTP binding protein 1 (GTPBP1)-like family includes GTPBP2
      cl27768
      Location:77 → 571
      SelB; Selenocysteine-specific translation elongation factor [Translation, ribosomal structure and biogenesis]

    4. XM_068216139.1 → XP_068072240.1  GTP-binding protein 1 isoform X4

      UniProtKB/TrEMBL
      Q6PFN0
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools