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    hoxb6a homeobox B6a [ Danio rerio (zebrafish) ]

    Gene ID: 30341, updated on 9-Dec-2024

    Summary

    Official Symbol
    hoxb6aprovided by ZNC
    Official Full Name
    homeobox B6aprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-990415-106
    See related
    Ensembl:ENSDARG00000010630 AllianceGenome:ZFIN:ZDB-GENE-990415-106
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    ZF22; z-39; ZF-22; hoxb6; hox-B6; hox-2.2
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in anterior/posterior pattern specification and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within regulation of DNA-templated transcription. Predicted to be active in nucleus. Is expressed in several structures, including lateral line system; mesoderm; neural plate; neural tube; and spinal cord. Orthologous to human HOXB6 (homeobox B6). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See hoxb6a in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 3 NC_007114.7 (23703704..23705444)
    105 previous assembly GRCz10 (GCF_000002035.5) 3 NC_007114.6 (23573156..23574896)

    Chromosome 3 - NC_007114.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC103910246 Neighboring gene homeobox B8a Neighboring gene homeobox B7a Neighboring gene homeobox B3a Neighboring gene homeobox B5a Neighboring gene microRNA 10c

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables DNA-binding transcription factor activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
     
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in anterior/posterior pattern specification IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    homeobox protein Hox-B6a
    Names
    homeo box B6a
    homeobox gene B-6
    homeobox protein Zf-22

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_131119.1NP_571194.1  homeobox protein Hox-B6a

      See identical proteins and their annotated locations for NP_571194.1

      Status: PROVISIONAL

      Source sequence(s)
      X17267
      UniProtKB/Swiss-Prot
      P15861, Q4PRA2, Q8AWY8
      Related
      ENSDARP00000002263.5, ENSDART00000024256.7
      Conserved Domains (1) summary
      pfam00046
      Location:154206
      Homeobox; Homeobox domain

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007114.7 Reference GRCz11 Primary Assembly

      Range
      23703704..23705444
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)