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    zgc:113518 zgc:113518 [ Danio rerio (zebrafish) ]

    Gene ID: 503531, updated on 9-Dec-2024

    Summary

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    Official Symbol
    zgc:113518provided by ZNC
    Official Full Name
    zgc:113518provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-050220-9
    See related
    Ensembl:ENSDARG00000015482 AllianceGenome:ZFIN:ZDB-GENE-050220-9
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Is expressed in myotome and pectoral fin musculature. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See zgc:113518 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 2 NC_007113.7 (176711..184051, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 2 NC_007113.6 (187800..195140, complement)

    Chromosome 2 - NC_007113.7Genomic Context describing neighboring genes Neighboring gene insulin-like growth factor binding protein 1b Neighboring gene adenylate cyclase 1b Neighboring gene Mov10 like RNA helicase 1 Neighboring gene zinc finger protein 1014 Neighboring gene zinc finger protein OZF

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Evolutionary and Expression Analysis of MOV10 and MOV10L1 Reveals Their Origin, Duplication and Divergence. Yang S, et al. Int J Mol Sci, 2022 Jul 7. PMID 35886872, Free PMC Article
    2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein LOC503531

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001012495.2 → NP_001012513.2  uncharacterized protein LOC503531

      See identical proteins and their annotated locations for NP_001012513.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 encode the same protein.
      Source sequence(s)
      BC090170, EH443748, EH469632
      UniProtKB/TrEMBL
      A0A8M1N4C5, F1QU11
      Related
      ENSDARP00000033134.6, ENSDART00000034783.8
      Conserved Domains (4) summary
      COG5048
      Location:63 → 225
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:69 → 89
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:67 → 89
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:249 → 274
      zf-H2C2_2; Zinc-finger double domain

    2. NM_001291323.1 → NP_001278252.1  uncharacterized protein LOC503531

      See identical proteins and their annotated locations for NP_001278252.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 encode the same protein.
      Source sequence(s)
      CABZ01064857, CABZ01064858
      UniProtKB/TrEMBL
      A0A8M1N4C5, F1QU11
      Related
      ENSDARP00000108035.2, ENSDART00000126704.3
      Conserved Domains (4) summary
      COG5048
      Location:63 → 225
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:69 → 89
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:67 → 89
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:249 → 274
      zf-H2C2_2; Zinc-finger double domain

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007113.7 Reference GRCz11 Primary Assembly

      Range
      176711..184051 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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