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    cep85 centrosomal protein 85 [ Danio rerio (zebrafish) ]

    Gene ID: 561994, updated on 9-Dec-2024

    Summary

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    Official Symbol
    cep85provided by ZNC
    Official Full Name
    centrosomal protein 85provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-1998
    See related
    Ensembl:ENSDARG00000060215 AllianceGenome:ZFIN:ZDB-GENE-030131-1998
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    fb94b04; wu:fb94b04; si:ch211-11i5.2
    Summary
    Predicted to be active in centrosome. Orthologous to human CEP85 (centrosomal protein 85). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See cep85 in Genome Data Viewer
    Location:
    chromosome: 16
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 16 NC_007127.7 (41684984..41714948, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 16 NC_007127.6 (41734949..41773174, complement)

    Chromosome 16 - NC_007127.7Genomic Context describing neighboring genes Neighboring gene ATPase secretory pathway Ca2+ transporting 1 Neighboring gene UBX domain protein 11 Neighboring gene uncharacterized LOC137487960 Neighboring gene si:dkey-199f5.8 Neighboring gene metadherin b

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Analysis of DNA methylation reveals a partial reprogramming of the Müller glia genome during retina regeneration. Powell C, et al. Proc Natl Acad Sci U S A, 2013 Dec 3. PMID 24248357, Free PMC Article
    2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Component Evidence Code Pubs
    is_active_in centrosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    coiled-coil domain-containing protein 21; centrosomal protein of 85 kDa

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007127.7 Reference GRCz11 Primary Assembly

      Range
      41684984..41714948 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_009292585.4 → XP_009290860.1  centrosomal protein of 85 kDa isoform X2

      UniProtKB/TrEMBL
      A0A8M3AJE9
      Conserved Domains (3) summary
      pfam04949
      Location:389 → 490
      Transcrip_act; Transcriptional activator
      pfam13870
      Location:319 → 509
      DUF4201; Domain of unknown function (DUF4201)
      cl12013
      Location:424 → 565
      BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

    2. XM_685394.10 → XP_690486.4  centrosomal protein of 85 kDa isoform X1

      UniProtKB/TrEMBL
      A0A8N7UVU8, E9QBC3
      Related
      ENSDARP00000119133.1, ENSDART00000138798.3
      Conserved Domains (3) summary
      pfam04949
      Location:389 → 490
      Transcrip_act; Transcriptional activator
      pfam13870
      Location:319 → 509
      DUF4201; Domain of unknown function (DUF4201)
      cl12013
      Location:424 → 565
      BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

    3. XM_068214214.1 → XP_068070315.1  centrosomal protein of 85 kDa isoform X3

      UniProtKB/TrEMBL
      A0A8M2B4L3

    4. XM_005158261.4 → XP_005158318.1  centrosomal protein of 85 kDa isoform X3

      See identical proteins and their annotated locations for XP_005158318.1

      UniProtKB/TrEMBL
      A0A8M2B4L3
      Conserved Domains (2) summary
      pfam13870
      Location:240 → 430
      DUF4201; Domain of unknown function (DUF4201)
      cl12013
      Location:345 → 486
      BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature
    Nucleotide Protein Strain
    Heading Accession and Version

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