ifngr2 interferon gamma receptor 2 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: ifngr2provided by ZNC
Official Full Name: interferon gamma receptor 2provided by ZNC
Primary source: ZFIN:ZDB-GENE-030131-5999
See related: Ensembl:ENSDARG00000067795 AllianceGenome:ZFIN:ZDB-GENE-030131-5999
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: crfb6; fi29f07; wu:fi29f07; si:ch211-254o18.4
Summary: Predicted to enable cytokine receptor activity. Predicted to be involved in cytokine-mediated signaling pathway. Predicted to be located in membrane. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in immunodeficiency 28. Orthologous to human IFNGR2 (interferon gamma receptor 2). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: chromosome: 5

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	5	NC_007116.7 (45889929..45894802, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	5	NC_007116.6 (45289776..45294616, complement)

Chromosome 5 - NC_007116.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help

See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

The receptor complex for Ifn-gamma2 includes cytokine receptor family B (Crfb)6 together with Crfb13 and Crfb17.
Title: In vivo analysis of Ifn-γ1 and Ifn-γ2 signaling in zebrafish.

Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables cytokine receptor activity	IBA Inferred from Biological aspect of Ancestor more info
enables cytokine receptor activity	ISS Inferred from Sequence or Structural Similarity more info	PubMed

Process	Evidence Code	Pubs
involved_in cytokine-mediated signaling pathway	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info
located_in membrane	NAS Non-traceable Author Statement more info	PubMed
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info

General protein information

Go to the top of the page Help

Preferred Names: interferon gamma receptor 2

Names: cytokine receptor family member b6

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001077627.2 → NP_001071095.2 interferon gamma receptor 2 precursor

Status: VALIDATED

Source sequence(s)

BX294131

UniProtKB/TrEMBL

A0FJI1

Related

ENSDARP00000088418.4, ENSDART00000097648.5

Conserved Domains (2) summary

smart00060
Location:24 → 96

FN3; Fibronectin type 3 domain

cl21522
Location:135 → 206

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...