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    uts2b urotensin 2, beta [ Danio rerio (zebrafish) ]

    Gene ID: 402853, updated on 9-Dec-2024

    Summary

    Official Symbol
    uts2bprovided by ZNC
    Official Full Name
    urotensin 2, betaprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040630-10
    See related
    Ensembl:ENSDARG00000017340 AllianceGenome:ZFIN:ZDB-GENE-040630-10
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Summary
    Predicted to enable hormone activity. Predicted to act upstream of or within blood vessel diameter maintenance and regulation of blood pressure. Predicted to be located in extracellular region. Is expressed in spinal cord. Human ortholog(s) of this gene implicated in gestational diabetes; hypertension; and type 2 diabetes mellitus. Orthologous to human UTS2 (urotensin 2). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See uts2b in Genome Data Viewer
    Location:
    chromosome: 11
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 11 NC_007122.7 (40024181..40030112, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 11 NC_007122.6 (39760036..39765967, complement)

    Chromosome 11 - NC_007122.7Genomic Context describing neighboring genes Neighboring gene vesicle-associated membrane protein 3 (cellubrevin) Neighboring gene period circadian clock 3 Neighboring gene coiled-coil domain containing 50b Neighboring gene tumor necrosis factor receptor superfamily, member 9b

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

    General gene information

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables hormone activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within blood vessel diameter maintenance IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within regulation of blood pressure IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    prepro-urotensin II-beta
    Names
    UII beta
    UII-b

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_205591.1NP_991154.1  prepro-urotensin II-beta precursor

      See identical proteins and their annotated locations for NP_991154.1

      Status: PROVISIONAL

      Source sequence(s)
      AY253851
      UniProtKB/Swiss-Prot
      Q7ZZY8
      UniProtKB/TrEMBL
      B3DFZ3
      Related
      ENSDARP00000006318.7, ENSDART00000021916.9

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007122.7 Reference GRCz11 Primary Assembly

      Range
      40024181..40030112 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)