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    nelfcd negative elongation factor complex member C/D [ Danio rerio (zebrafish) ]

    Gene ID: 394165, updated on 9-Dec-2024

    Summary

    Official Symbol
    nelfcdprovided by ZNC
    Official Full Name
    negative elongation factor complex member C/Dprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040426-720
    See related
    Ensembl:ENSDARG00000021097 AllianceGenome:ZFIN:ZDB-GENE-040426-720
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    th1l; zgc:55482
    Summary
    Predicted to enable RNA binding activity. Predicted to be involved in negative regulation of transcription elongation by RNA polymerase II. Predicted to act upstream of or within negative regulation of DNA-templated transcription and translational elongation. Predicted to be located in nucleus. Predicted to be part of NELF complex. Orthologous to human NELFCD (negative elongation factor complex member C/D). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See nelfcd in Genome Data Viewer
    Location:
    chromosome: 6
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 6 NC_007117.7 (49782380..49801132, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 6 NC_007117.6 (49783727..49802479, complement)

    Chromosome 6 - NC_007117.7Genomic Context describing neighboring genes Neighboring gene si:dkey-249d8.1 Neighboring gene cathepsin Z Neighboring gene GNAS complex locus Neighboring gene tubulin, beta 1 class VI

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Clone Names

    • MGC55482

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables translation elongation factor activity IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    part_of NELF complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    negative elongation factor C/D
    Names
    TH1-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_201190.1NP_957484.1  negative elongation factor C/D

      See identical proteins and their annotated locations for NP_957484.1

      Status: PROVISIONAL

      Source sequence(s)
      BC045357
      UniProtKB/TrEMBL
      Q7ZVZ0
      Related
      ENSDARP00000021861.6, ENSDART00000008959.7
      Conserved Domains (1) summary
      pfam04858
      Location:2576
      TH1; TH1 protein

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007117.7 Reference GRCz11 Primary Assembly

      Range
      49782380..49801132 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)