psmb5 proteasome 20S subunit beta 5 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: psmb5provided by ZNC
Official Full Name: proteasome 20S subunit beta 5provided by ZNC
Primary source: ZFIN:ZDB-GENE-990415-215
See related: Ensembl:ENSDARG00000075445 AllianceGenome:ZFIN:ZDB-GENE-990415-215
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: x; beta5; zgc:86820; wu:fb59c07; etID309919.2; si:zc14a17.13
Summary: Predicted to enable endopeptidase activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Predicted to act upstream of or within proteolysis involved in protein catabolic process. Predicted to be located in cytoplasm. Predicted to be part of proteasome core complex, beta-subunit complex. Predicted to be active in cytosol and nucleus. Is expressed in female organism. Orthologous to human PSMB5 (proteasome 20S subunit beta 5). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 2

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	2	NC_007113.7 (38373273..38392579)
105	previous assembly	GRCz10 (GCF_000002035.5)	2	NC_007113.6 (38390945..38410251)

Chromosome 2 - NC_007113.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

fb59c07.x1 (e-PCR)
- UniSTS:203343

psmx (e-PCR)
- UniSTS:187022

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables endopeptidase activity	IBA Inferred from Biological aspect of Ancestor more info
enables threonine-type endopeptidase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in proteasome-mediated ubiquitin-dependent protein catabolic process	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within proteolysis involved in protein catabolic process	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
is_active_in cytosol	IBA Inferred from Biological aspect of Ancestor more info
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleus	IEA Inferred from Electronic Annotation more info
part_of proteasome complex	IEA Inferred from Electronic Annotation more info
part_of proteasome core complex	IEA Inferred from Electronic Annotation more info
part_of proteasome core complex, beta-subunit complex	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: proteasome subunit beta type-5

Names: proteasome (prosome, macropain) subunit, beta type, 5; proteasome subunit X; proteasome subunit beta 5

NP_571226.1

EC 3.4.25.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_131151.1 → NP_571226.1 proteasome subunit beta type-5

See identical proteins and their annotated locations for NP_571226.1

Status: PROVISIONAL

Source sequence(s)

BC071478

UniProtKB/TrEMBL

Q6IQD0

Related

ENSDARP00000099755.2, ENSDART00000113111.3

Conserved Domains (2) summary

PTZ00488
Location:44 → 268

PTZ00488; Proteasome subunit beta type-5; Provisional

cd03761
Location:66 → 253

proteasome_beta_type_5; proteasome beta type-5 subunit. The 20S proteasome, multisubunit proteolytic complex, is the central enzyme of nonlysosomal protein degradation in both the cytosol and nucleus. It is composed of 28 subunits arranged as four homoheptameric rings that ...