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    btaf1 BTAF1 RNA polymerase II, B-TFIID transcription factor-associated [ Danio rerio (zebrafish) ]

    Gene ID: 565357, updated on 4-Jan-2025

    Summary

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    Official Symbol
    btaf1provided by ZNC
    Official Full Name
    BTAF1 RNA polymerase II, B-TFIID transcription factor-associatedprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-021025-1
    See related
    Ensembl:ENSDARG00000060089 AllianceGenome:ZFIN:ZDB-GENE-021025-1
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    TAFII; wu:fd60h10; wu:fe26c12
    Summary
    Predicted to enable several functions, including ATP binding activity; ATP hydrolysis activity; and TBP-class protein binding activity. Predicted to be located in nucleus. Orthologous to human BTAF1 (B-TFIID TATA-box binding protein associated factor 1). [provided by Alliance of Genome Resources, Jan 2025]
    Orthologs
    human mouse all
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    Genomic context

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    See btaf1 in Genome Data Viewer
    Location:
    chromosome: 13
    Exon count:
    38
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 13 NC_007124.7 (42480852..42536960, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 13 NC_007124.6 (42354792..42410934, complement)

    Chromosome 13 - NC_007124.7Genomic Context describing neighboring genes Neighboring gene insulin-degrading enzyme Neighboring gene membrane-associated ring finger (C3HC4) 5 Neighboring gene cytoplasmic polyadenylation element binding protein 3 Neighboring gene si:dkey-221j11.3 Neighboring gene androgen-dependent TFPI-regulating protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Molecular cloning and developmental expression of Tlx (Hox11) genes in zebrafish (Danio rerio). Langenau DM, et al. Mech Dev, 2002 Sep. PMID 12204264
    2. A network of epigenetic regulators guides developmental haematopoiesis in vivo. Huang HT, et al. Nat Cell Biol, 2013 Dec. PMID 24240475, Free PMC Article
    3. Hematopoietic gene expression profile in zebrafish kidney marrow. Song HD, et al. Proc Natl Acad Sci U S A, 2004 Nov 16. PMID 15520368, Free PMC Article
    4. The zebrafish gene map defines ancestral vertebrate chromosomes. Woods IG, et al. Genome Res, 2005 Sep. PMID 16109975, Free PMC Article
    5. 15000 unique zebrafish EST clusters and their future use in microarray for profiling gene expression patterns during embryogenesis. Lo J, et al. Genome Res, 2003 Mar. PMID 12618376, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP-dependent chromatin remodeler activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables TBP-class protein binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables helicase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    TATA-binding protein-associated factor 172
    Names
    BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007124.7 Reference GRCz11 Primary Assembly

      Range
      42480852..42536960 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005169532.5 → XP_005169589.1  TATA-binding protein-associated factor 172

      UniProtKB/TrEMBL
      A0A8M2BGW0
      Related
      ENSDARP00000121068.1, ENSDART00000134533.3
      Conserved Domains (5) summary
      cd00046
      Location:1296 → 1445
      DEXDc; DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
      cd00079
      Location:1625 → 1762
      HELICc; Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may ...
      pfam00176
      Location:1279 → 1595
      SNF2_N; SNF2 family N-terminal domain
      pfam12054
      Location:595 → 1062
      DUF3535; Domain of unknown function (DUF3535)
      sd00044
      Location:1063 → 1100
      HEAT; HEAT repeat [structural motif]

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001159406.1: Suppressed sequence

      Description
      NM_001159406.1: This RefSeq record was removed by NCBI staff. Contact [email protected] for further information.
    Nucleotide Protein Strain
    Heading Accession and Version

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