mt-co1 cytochrome c oxidase I, mitochondrial [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: mt-co1provided by ZNC
Official Full Name: cytochrome c oxidase I, mitochondrialprovided by ZNC
Primary source: ZFIN:ZDB-GENE-011205-14
See related: AllianceGenome:ZFIN:ZDB-GENE-011205-14
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: mtco1; COX1
Summary: Predicted to enable copper ion binding activity; heme binding activity; and oxidoreduction-driven active transmembrane transporter activity. Predicted to contribute to cytochrome-c oxidase activity. Acts upstream of or within response to cadmium ion and response to methylmercury. Predicted to be located in mitochondrial inner membrane. Predicted to be part of respiratory chain complex IV. Is expressed in several structures, including female organism; gill; liver; male organism; and musculature system. Orthologous to human MT-CO1 (mitochondrially encoded cytochrome c oxidase I). [provided by Alliance of Genome Resources, Dec 2024]
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Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	MT (non-nuclear)	NC_002333.2 (6425..7975)
105	previous assembly	GRCz10 (GCF_000002035.5)	MT (non-nuclear)	NC_002333.2 (6425..7975)

Chromosome MT - NC_002333.2 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

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Function	Evidence Code	Pubs
enables NADH dehydrogenase (ubiquinone) activity	IEA Inferred from Electronic Annotation more info
enables copper ion binding	IEA Inferred from Electronic Annotation more info
contributes_to cytochrome-c oxidase activity	IBA Inferred from Biological aspect of Ancestor more info
enables cytochrome-c oxidase activity	IEA Inferred from Electronic Annotation more info
enables electron transfer activity	IEA Inferred from Electronic Annotation more info
enables heme binding	IEA Inferred from Electronic Annotation more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables oxidoreductase activity	IEA Inferred from Electronic Annotation more info
enables oxidoreductase activity, acting on NAD(P)H	IEA Inferred from Electronic Annotation more info
enables proton transmembrane transporter activity	IEA Inferred from Electronic Annotation more info
enables ubiquinol-cytochrome-c reductase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within ATP synthesis coupled electron transport	IEA Inferred from Electronic Annotation more info
involved_in aerobic respiration	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within aerobic respiration	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within electron transport chain	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within mitochondrial electron transport, NADH to ubiquinone	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within proton motive force-driven ATP synthesis	IEA Inferred from Electronic Annotation more info
involved_in respiratory electron transport chain	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within respiratory electron transport chain	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within response to cadmium ion	IEP Inferred from Expression Pattern more info	PubMed
acts_upstream_of_or_within response to methylmercury	IDA Inferred from Direct Assay more info	PubMed

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info
located_in mitochondrial inner membrane	IEA Inferred from Electronic Annotation more info
located_in mitochondrion	IEA Inferred from Electronic Annotation more info
part_of proton-transporting ATP synthase complex, coupling factor F(o)	IEA Inferred from Electronic Annotation more info
part_of respiratory chain complex III	IEA Inferred from Electronic Annotation more info
part_of respiratory chain complex IV	IBA Inferred from Biological aspect of Ancestor more info
part_of respiratory chain complex IV	IEA Inferred from Electronic Annotation more info
part_of respiratory chain complex IV	ISS Inferred from Sequence or Structural Similarity more info

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