ibtk inhibitor of Bruton agammaglobulinemia tyrosine kinase [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: ibtkprovided by ZNC
Official Full Name: inhibitor of Bruton agammaglobulinemia tyrosine kinaseprovided by ZNC
Primary source: ZFIN:ZDB-GENE-030131-6246
See related: Ensembl:ENSDARG00000074424 AllianceGenome:ZFIN:ZDB-GENE-030131-6246
Gene type: protein coding
RefSeq status: MODEL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: fi40c08; wu:fi40c08
Summary: Predicted to enable protein kinase binding activity and protein tyrosine kinase inhibitor activity. Predicted to be involved in release of sequestered calcium ion into cytosol. Predicted to act upstream of or within phosphorylation. Predicted to be active in cytoplasm and nucleoplasm. Is expressed in telencephalon. Orthologous to human IBTK (inhibitor of Bruton tyrosine kinase). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human mouse all
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Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	16	NC_007127.7 (4839073..4896066)
105	previous assembly	GRCz10 (GCF_000002035.5)	16	NC_007127.6 (5009789..5067059)

Chromosome 16 - NC_007127.7 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Submit: New GeneRIF Correction

Function	Evidence Code	Pubs
enables kinase activity	IEA Inferred from Electronic Annotation more info
enables protein kinase binding	IBA Inferred from Biological aspect of Ancestor more info
enables protein tyrosine kinase inhibitor activity	IBA Inferred from Biological aspect of Ancestor more info
enables transferase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within phosphorylation	IEA Inferred from Electronic Annotation more info
involved_in release of sequestered calcium ion into cytosol	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
is_active_in nucleoplasm	IBA Inferred from Biological aspect of Ancestor more info

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The following sections contain reference sequences that belong to a specific genome build. Explain