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    rab35a RAB35, member RAS oncogene family a [ Danio rerio (zebrafish) ]

    Gene ID: 796454, updated on 9-Dec-2024

    Summary

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    Official Symbol
    rab35aprovided by ZNC
    Official Full Name
    RAB35, member RAS oncogene family aprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-131030-1
    See related
    Ensembl:ENSDARG00000102078 AllianceGenome:ZFIN:ZDB-GENE-131030-1
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    rab35
    Summary
    Predicted to enable GTP binding activity and GTPase activity. Is expressed in telencephalon. Orthologous to human RAB35 (RAB35, member RAS oncogene family). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See rab35a in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 5 NC_007116.7 (2651632..2676325, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 5 NC_007116.6 (2486003..2510698)

    Chromosome 5 - NC_007116.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC137495508 Neighboring gene carbonic anhydrase IV a Neighboring gene myotubularin related protein 4 Neighboring gene uncharacterized LOC103910293 Neighboring gene citron rho-interacting serine/threonine kinase a Neighboring gene guanine nucleotide binding protein (G protein), gamma 10 Neighboring gene Rab9 effector protein with kelch motifs

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Rab8, Rab11, and Rab35 coordinate lumen and cilia formation during zebrafish left-right organizer development. Aljiboury AA, et al. PLoS Genet, 2023 May. PMID 37186603, Free PMC Article
    2. A plasmid library of full-length zebrafish rab proteins for in vivo cell biology. Hall TE, et al. Cell Logist, 2017. PMID 28396820, Free PMC Article
    3. Comprehensive expression map of transcription regulators in the adult zebrafish telencephalon reveals distinct neurogenic niches. Diotel N, et al. J Comp Neurol, 2015 Jun 1. PMID 25556858, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Rab8, Rab11, and Rab35 coordinate lumen and cilia formation during zebrafish left-right organizer development.
      Title: Rab8, Rab11, and Rab35 coordinate lumen and cilia formation during zebrafish left-right organizer development.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables GTP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    ras-related protein Rab-35

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001386745.1 → NP_001373674.1  ras-related protein Rab-35

      Status: VALIDATED

      Source sequence(s)
      CABZ01072548, CABZ01072549
      UniProtKB/TrEMBL
      A0A0G2L264, A0A8M1PRX4
      Related
      ENSDARP00000138829.1, ENSDART00000159661.2
      Conserved Domains (1) summary
      cl38936
      Location:3 → 176
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007116.7 Reference GRCz11 Primary Assembly

      Range
      2651632..2676325 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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