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    tsr2 TSR2 ribosome maturation factor [ Danio rerio (zebrafish) ]

    Gene ID: 317639, updated on 9-Dec-2024

    Summary

    Official Symbol
    tsr2provided by ZNC
    Official Full Name
    TSR2 ribosome maturation factorprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-021231-2
    See related
    Ensembl:ENSDARG00000005772 AllianceGenome:ZFIN:ZDB-GENE-021231-2
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    chunp6926; dt1p1a10l; zgc:109784
    Summary
    Predicted to be involved in maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Predicted to act upstream of or within rRNA processing. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in Diamond-Blackfan anemia 14 with mandibulofacial dysostosis. Orthologous to human TSR2 (TSR2 ribosome maturation factor). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See tsr2 in Genome Data Viewer
    Location:
    chromosome: 8
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 8 NC_007119.7 (8341082..8349653, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 8 NC_007119.6 (8302497..8311088, complement)

    Chromosome 8 - NC_007119.7Genomic Context describing neighboring genes Neighboring gene plexin B3 Neighboring gene SRSF protein kinase 3 Neighboring gene cyclin dependent kinase 16 Neighboring gene uncharacterized LOC137496291

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General protein information

    Preferred Names
    pre-rRNA-processing protein TSR2 homolog
    Names
    TSR2, 20S rRNA accumulation, homolog
    hypothetical protein DT1P1A10 - like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_173284.3NP_775391.1  pre-rRNA-processing protein TSR2 homolog

      See identical proteins and their annotated locations for NP_775391.1

      Status: PROVISIONAL

      Source sequence(s)
      BC078277
      UniProtKB/TrEMBL
      Q8JGT2
      Related
      ENSDARP00000026184.7, ENSDART00000025214.9
      Conserved Domains (1) summary
      pfam10273
      Location:1291
      WGG; Pre-rRNA-processing protein TSR2

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007119.7 Reference GRCz11 Primary Assembly

      Range
      8341082..8349653 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)