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    ical1 islet cell autoantigen 1-like [ Danio rerio (zebrafish) ]

    Gene ID: 378720, updated on 9-Dec-2024

    Summary

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    Official Symbol
    ical1provided by ZNC
    Official Full Name
    islet cell autoantigen 1-likeprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030910-4
    See related
    Ensembl:ENSDARG00000057688 AllianceGenome:ZFIN:ZDB-GENE-030910-4
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    ica; cb781; wu:fi39e04
    Summary
    Predicted to enable protein domain specific binding activity. Predicted to be involved in regulation of transport. Predicted to be active in Golgi apparatus. Is expressed in central nervous system; hatching gland; and polster. Orthologous to human ICA1L (islet cell autoantigen 1 like). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See ical1 in Genome Data Viewer
    Location:
    chromosome: 6
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 6 NC_007117.7 (12869769..12900184, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 6 NC_007117.6 (12634911..12665357, complement)

    Chromosome 6 - NC_007117.7Genomic Context describing neighboring genes Neighboring gene bone morphogenetic protein receptor, type II a (serine/threonine kinase) Neighboring gene family with sequence similarity 117 member Ba Neighboring gene uncharacterized LOC137495929 Neighboring gene chemokine (C-X-C motif) receptor 4a

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. The zebrafish gene map defines ancestral vertebrate chromosomes. Woods IG, et al. Genome Res, 2005 Sep. PMID 16109975, Free PMC Article
    2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables protein domain specific binding IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    islet cell autoantigen 1-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_201587.1 → NP_963881.1  islet cell autoantigen 1-like

      See identical proteins and their annotated locations for NP_963881.1

      Status: PROVISIONAL

      Source sequence(s)
      BC044404
      UniProtKB/TrEMBL
      Q803N6
      Related
      ENSDARP00000074858.5, ENSDART00000080408.7
      Conserved Domains (2) summary
      cd07661
      Location:54 → 257
      BAR_ICA69; The Bin/Amphiphysin/Rvs (BAR) domain of Islet Cell Autoantigen 69-kDa
      pfam04629
      Location:431 → 569
      ICA69; Islet cell autoantigen ICA69, C-terminal domain

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007117.7 Reference GRCz11 Primary Assembly

      Range
      12869769..12900184 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021476797.2 → XP_021332472.1  islet cell autoantigen 1-like isoform X8

      UniProtKB/TrEMBL
      A0A8M9PLX1
      Conserved Domains (2) summary
      cd07661
      Location:54 → 257
      BAR_ICA69; The Bin/Amphiphysin/Rvs (BAR) domain of Islet Cell Autoantigen 69-kDa
      pfam04629
      Location:262 → 497
      ICA69; Islet cell autoantigen ICA69, C-terminal domain

    2. XM_068221661.1 → XP_068077762.1  islet cell autoantigen 1-like isoform X7

    3. XM_005165831.5 → XP_005165888.1  islet cell autoantigen 1-like isoform X4

      UniProtKB/TrEMBL
      A0A8M2BD37
      Conserved Domains (2) summary
      cd07661
      Location:54 → 257
      BAR_ICA69; The Bin/Amphiphysin/Rvs (BAR) domain of Islet Cell Autoantigen 69-kDa
      pfam04629
      Location:430 → 568
      ICA69; Islet cell autoantigen ICA69, C-terminal domain

    4. XM_005165827.5 → XP_005165884.1  islet cell autoantigen 1-like isoform X3

      UniProtKB/TrEMBL
      A0A8M2BDB5, F1QC36
      Conserved Domains (2) summary
      cd07661
      Location:54 → 257
      BAR_ICA69; The Bin/Amphiphysin/Rvs (BAR) domain of Islet Cell Autoantigen 69-kDa
      pfam04629
      Location:431 → 569
      ICA69; Islet cell autoantigen ICA69, C-terminal domain

    5. XM_009302230.4 → XP_009300505.1  islet cell autoantigen 1-like isoform X6

      UniProtKB/TrEMBL
      A0A8M3BA90
      Conserved Domains (2) summary
      cd07661
      Location:54 → 257
      BAR_ICA69; The Bin/Amphiphysin/Rvs (BAR) domain of Islet Cell Autoantigen 69-kDa
      pfam04629
      Location:262 → 514
      ICA69; Islet cell autoantigen ICA69, C-terminal domain

    6. XM_009302229.4 → XP_009300504.1  islet cell autoantigen 1-like isoform X5

      UniProtKB/TrEMBL
      A0A8M3AT71
      Conserved Domains (2) summary
      cd07661
      Location:54 → 257
      BAR_ICA69; The Bin/Amphiphysin/Rvs (BAR) domain of Islet Cell Autoantigen 69-kDa
      pfam04629
      Location:262 → 515
      ICA69; Islet cell autoantigen ICA69, C-terminal domain

    7. XM_009302228.4 → XP_009300503.1  islet cell autoantigen 1-like isoform X2

      UniProtKB/TrEMBL
      A0A8M3B0A0
      Conserved Domains (2) summary
      cd07661
      Location:54 → 257
      BAR_ICA69; The Bin/Amphiphysin/Rvs (BAR) domain of Islet Cell Autoantigen 69-kDa
      pfam04629
      Location:447 → 585
      ICA69; Islet cell autoantigen ICA69, C-terminal domain

    8. XM_009302222.4 → XP_009300497.1  islet cell autoantigen 1-like isoform X1

      See identical proteins and their annotated locations for XP_009300497.1

      UniProtKB/TrEMBL
      A0A8M3AT72
      Conserved Domains (2) summary
      cd07661
      Location:54 → 257
      BAR_ICA69; The Bin/Amphiphysin/Rvs (BAR) domain of Islet Cell Autoantigen 69-kDa
      pfam04629
      Location:448 → 586
      ICA69; Islet cell autoantigen ICA69, C-terminal domain

    9. XM_009302224.4 → XP_009300499.1  islet cell autoantigen 1-like isoform X1

      See identical proteins and their annotated locations for XP_009300499.1

      UniProtKB/TrEMBL
      A0A8M3AT72
      Conserved Domains (2) summary
      cd07661
      Location:54 → 257
      BAR_ICA69; The Bin/Amphiphysin/Rvs (BAR) domain of Islet Cell Autoantigen 69-kDa
      pfam04629
      Location:448 → 586
      ICA69; Islet cell autoantigen ICA69, C-terminal domain
    Nucleotide Protein Strain
    Heading Accession and Version

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