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    abcc10 ATP-binding cassette, sub-family C (CFTR/MRP), member 10 [ Danio rerio (zebrafish) ]

    Gene ID: 556709, updated on 9-Dec-2024

    Summary

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    Official Symbol
    abcc10provided by ZNC
    Official Full Name
    ATP-binding cassette, sub-family C (CFTR/MRP), member 10provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-050517-24
    See related
    Ensembl:ENSDARG00000077988 AllianceGenome:ZFIN:ZDB-GENE-050517-24
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    si:ch211-69b7.2
    Summary
    Predicted to enable ABC-type transporter activity; ATP binding activity; and ATP hydrolysis activity. Predicted to act upstream of or within transmembrane transport. Predicted to be located in membrane. Orthologous to human ABCC10 (ATP binding cassette subfamily C member 10). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See abcc10 in Genome Data Viewer
    Location:
    chromosome: 11
    Exon count:
    23
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 11 NC_007122.7 (11911399..11964702, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 11 NC_007122.6 (11927854..11978136, complement)

    Chromosome 11 - NC_007122.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC137490405 Neighboring gene WAS/WASL interacting protein family, member 2a Neighboring gene serine/threonine-protein kinase pim-2-like Neighboring gene si:ch211-69b7.6 Neighboring gene zgc:64002 Neighboring gene sp2 transcription factor

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. A New Zebrafish Model for Pseudoxanthoma Elasticum. Czimer D, et al. Front Cell Dev Biol, 2021. PMID 33768091, Free PMC Article
    2. Evolution of the vertebrate ABC gene family: analysis of gene birth and death. Annilo T, et al. Genomics, 2006 Jul. PMID 16631343
    3. Evolution of the ATP-binding cassette (ABC) transporter superfamily in vertebrates. Dean M, et al. Annu Rev Genomics Hum Genet, 2005. PMID 16124856
    4. Genome-wide analysis of the ATP-binding cassette (ABC) transporter gene family in sea lamprey and Japanese lamprey. Ren J, et al. BMC Genomics, 2015 Jun 6. PMID 26047617, Free PMC Article
    5. Expression and regulation of drug transporters in vertebrate neutrophils. Foulkes MJ, et al. Sci Rep, 2017 Jul 10. PMID 28694436, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables ABC-type transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATPase-coupled transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    ATP-binding cassette sub-family C member 10

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007122.7 Reference GRCz11 Primary Assembly

      Range
      11911399..11964702 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_068224297.1 → XP_068080398.1  ATP-binding cassette sub-family C member 10

      UniProtKB/TrEMBL
      A0A8M9PSA7, E7F961

    2. XM_021479750.2 → XP_021335425.1  ATP-binding cassette sub-family C member 10

      UniProtKB/TrEMBL
      A0A8M9PSA7, E7F961
      Related
      ENSDARP00000101288.2, ENSDART00000115249.4
      Conserved Domains (1) summary
      cl26602
      Location:248 → 1531
      SunT; ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms]

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018394803.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      20022..73325 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_068218641.1 → XP_068074742.1  ATP-binding cassette sub-family C member 10

      UniProtKB/TrEMBL
      A0A8M9PSA7, E7F961

    2. XM_005155760.5 → XP_005155817.1  ATP-binding cassette sub-family C member 10

      UniProtKB/TrEMBL
      A0A8M9PSA7, E7F961
      Conserved Domains (1) summary
      cl26602
      Location:248 → 1531
      SunT; ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms]

    Reference GRCz11 ALT_DRER_TU_2

    Genomic

    1. NW_018395295.1 Reference GRCz11 ALT_DRER_TU_2

      Range
      20022..73325 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_068219295.1 → XP_068075396.1  ATP-binding cassette sub-family C member 10

      UniProtKB/TrEMBL
      A0A8M9PSA7, E7F961

    2. XM_021474228.2 → XP_021329903.1  ATP-binding cassette sub-family C member 10

      UniProtKB/TrEMBL
      A0A8M9PSA7, E7F961
      Conserved Domains (1) summary
      cl26602
      Location:248 → 1531
      SunT; ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms]
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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