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    ifi44f1 interferon induced protein 44f1 [ Danio rerio (zebrafish) ]

    Gene ID: 555357, updated on 9-Dec-2024

    Summary

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    Official Symbol
    ifi44f1provided by ZNC
    Official Full Name
    interferon induced protein 44f1provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-050208-617
    See related
    Ensembl:ENSDARG00000071361 AllianceGenome:ZFIN:ZDB-GENE-050208-617
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    si:ch211-197g15.10
    Summary
    Predicted to enable GTP binding activity. Predicted to be involved in immune response. Orthologous to several human genes including IFI44L (interferon induced protein 44 like). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See ifi44f1 in Genome Data Viewer
    Location:
    chromosome: 22
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 22 NC_007133.7 (17455654..17459620, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 22 NC_007133.6 (17428638..17434633, complement)

    Chromosome 22 - NC_007133.7Genomic Context describing neighboring genes Neighboring gene family with sequence similarity 163 member Ab Neighboring gene RAB GTPase activating protein 1-like Neighboring gene G protein-coupled receptor 52 Neighboring gene si:ch211-197g15.9 Neighboring gene interferon induced protein 44f3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Excessive R-loops trigger an inflammatory cascade leading to increased HSPC production. Weinreb JT, et al. Dev Cell, 2021 Mar 8. PMID 33651979, Free PMC Article
    2. IFN-Stimulated Genes in Zebrafish and Humans Define an Ancient Arsenal of Antiviral Immunity. Levraud JP, et al. J Immunol, 2019 Dec 15. PMID 31732531
    3. Contrasted innate responses to two viruses in zebrafish: insights into the ancestral repertoire of vertebrate IFN-stimulated genes. Briolat V, et al. J Immunol, 2014 May 1. PMID 24683187
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables GTP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in immune response IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    interferon induced protein 44f1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001128684.1 → NP_001122156.1  interferon induced protein 44f1

      See identical proteins and their annotated locations for NP_001122156.1

      Status: PROVISIONAL

      Source sequence(s)
      BC163657
      UniProtKB/TrEMBL
      A7MBS6, B3DJY8
      Related
      ENSDARP00000121020.1, ENSDART00000142267.2
      Conserved Domains (2) summary
      cd00882
      Location:231 → 418
      Ras_like_GTPase; Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases)
      pfam07534
      Location:41 → 180
      TLD; TLD

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007133.7 Reference GRCz11 Primary Assembly

      Range
      17455654..17459620 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017353145.3 → XP_017208634.1  interferon induced protein 44f1 isoform X1

      UniProtKB/TrEMBL
      A0A8M6Z430, A7MBS6
    Nucleotide Protein Strain
    Heading Accession and Version

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