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    zgc:86839 zgc:86839 [ Danio rerio (zebrafish) ]

    Gene ID: 415200, updated on 9-Dec-2024

    Summary

    Official Symbol
    zgc:86839provided by ZNC
    Official Full Name
    zgc:86839provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040625-102
    See related
    Ensembl:ENSDARG00000117089 AllianceGenome:ZFIN:ZDB-GENE-040625-102
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Summary
    Predicted to enable several functions, including cyclin-dependent protein serine/threonine kinase activator activity; histone binding activity; and ubiquitin binding activity. Predicted to be involved in regulation of mitotic cell cycle. Predicted to be part of SCF ubiquitin ligase complex and cyclin-dependent protein kinase holoenzyme complex. Orthologous to human CKS2 (CDC28 protein kinase regulatory subunit 2). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See zgc:86839 in Genome Data Viewer
    Location:
    chromosome: 21
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 21 NC_007132.7 (3003753..3007412, complement)

    Chromosome 21 - NC_007132.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC137488860 Neighboring gene uncharacterized LOC110438219 Neighboring gene si:ch211-248k15.5 Neighboring gene uncharacterized LOC100150791 Neighboring gene ribonuclease inhibitor-like

    Genomic regions, transcripts, and products

    Genomic Sequence:
    NC_007132.7 Chromosome 21 Reference GRCz11 Primary Assembly

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables cyclin-dependent protein serine/threonine kinase activator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables cyclin-dependent protein serine/threonine kinase regulator activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables histone binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables protein kinase binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables ubiquitin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within cell division IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in cell division IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in regulation of mitotic cell cycle IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    part_of SCF ubiquitin ligase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of cyclin-dependent protein kinase holoenzyme complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    Cyclin-dependent kinases regulatory subunit 2-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001002110.1NP_001002110.1  Cyclin-dependent kinases regulatory subunit 2-like

      See identical proteins and their annotated locations for NP_001002110.1

      Status: PROVISIONAL

      Source sequence(s)
      BC071486
      UniProtKB/TrEMBL
      Q6IQC3
      Related
      ENSDARP00000144674.1, ENSDART00000190839.1
      Conserved Domains (1) summary
      pfam01111
      Location:873
      CKS; Cyclin-dependent kinase regulatory subunit

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007132.7 Reference GRCz11 Primary Assembly

      Range
      3003753..3007412 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)