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    bcl2l10 BCL2 like 10 [ Danio rerio (zebrafish) ]

    Gene ID: 373113, updated on 9-Dec-2024

    Summary

    Official Symbol
    bcl2l10provided by ZNC
    Official Full Name
    BCL2 like 10provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030825-2
    See related
    AllianceGenome:ZFIN:ZDB-GENE-030825-2
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    nr13; NR-13; mcl1l; sb:cb78
    Summary
    Predicted to enable channel activity. Acts upstream of or within several processes, including calcium-mediated signaling; epiboly; and somitogenesis. Located in mitochondrion. Is expressed in several structures, including digestive system; margin; mesoderm; nervous system; and yolk syncytial layer. Human ortholog(s) of this gene implicated in multiple myeloma; myelodysplastic syndrome; and stomach carcinoma. Orthologous to human BCL2L10 (BCL2 like 10). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See bcl2l10 in Genome Data Viewer
    Location:
    chromosome: 18
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 18 NC_007129.7 (39106710..39119007)
    105 previous assembly GRCz10 (GCF_000002035.5) 18 NC_007129.6 (39125726..39137999)

    Chromosome 18 - NC_007129.7Genomic Context describing neighboring genes Neighboring gene zgc:171509 Neighboring gene guanine nucleotide binding protein (G protein), beta 5b Neighboring gene uncharacterized LOC137488228 Neighboring gene mitogen-activated protein kinase 6

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    General gene information

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables channel activity  
    enables protein binding PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within apoptotic process  
    acts_upstream_of_or_within calcium-mediated signaling PubMed 
    acts_upstream_of_or_within epiboly PubMed 
    involved_in extrinsic apoptotic signaling pathway in absence of ligand  
    acts_upstream_of_or_within gastrulation PubMed 
    acts_upstream_of_or_within gastrulation PubMed 
    involved_in intrinsic apoptotic signaling pathway in response to DNA damage  
    acts_upstream_of_or_within negative regulation of apoptotic process PubMed 
    acts_upstream_of_or_within negative regulation of apoptotic process PubMed 
    acts_upstream_of_or_within negative regulation of apoptotic process PubMed 
    involved_in positive regulation of apoptotic process  
    acts_upstream_of_or_within regulation of apoptotic process  
    acts_upstream_of_or_within regulation of release of sequestered calcium ion into cytosol PubMed 
    involved_in release of cytochrome c from mitochondria  
    acts_upstream_of_or_within somitogenesis PubMed 
    Component Evidence Code Pubs
    located_in membrane  
    is_active_in mitochondrial outer membrane  
    located_in mitochondrion PubMed 

    General protein information

    Preferred Names
    bcl-2-like protein 10
    Names
    BCL2-like 10 (apoptosis facilitator)
    Boo/DIVA
    nrz

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_194398.3 → NP_919379.2  bcl-2-like protein 10

      Status: VALIDATED

      Source sequence(s)
      BI984816, CK696327, EH471672
      UniProtKB/TrEMBL
      F6NVG2, Q3B7G0, Q8UWD5

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007129.7 Reference GRCz11 Primary Assembly

      Range
      39106710..39119007
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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