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    si:dkey-127k13.1 si:dkey-127k13.1 [ Danio rerio (zebrafish) ]

    Gene ID: 100007612, updated on 9-Dec-2024

    Summary

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    Official Symbol
    si:dkey-127k13.1provided by ZNC
    Official Full Name
    si:dkey-127k13.1provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-070912-368
    See related
    AllianceGenome:ZFIN:ZDB-GENE-070912-368
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    fj78g08; im:6911747; wu:fj78g08
    Summary
    Predicted to enable DNA binding activity. Orthologous to several human genes including PWWP3A (PWWP domain containing 3A, DNA repair factor) and PWWP3B (PWWP domain containing 3B). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See si:dkey-127k13.1 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 2 NC_007113.7 (37449294..37462453, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 2 NC_007113.6 (37466839..37480017, complement)

    Chromosome 2 - NC_007113.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC137487478 Neighboring gene polyhomeotic homolog 3 (Drosophila) Neighboring gene death-associated protein kinase 3 Neighboring gene signal peptide peptidase-like 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. The Zebrafish Equivalent of Alzheimer's Disease-Associated PRESENILIN Isoform PS2V Regulates Inflammatory and Other Responses to Hypoxic Stress. Ebrahimie E, et al. J Alzheimers Dis, 2016 Mar 31. PMID 27031468
    2. 15000 unique zebrafish EST clusters and their future use in microarray for profiling gene expression patterns during embryogenesis. Lo J, et al. Genome Res, 2003 Mar. PMID 12618376, Free PMC Article
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    PWWP domain-containing protein MUM1; serine/arginine repetitive matrix protein 1
    Names
    melanoma associated antigen (mutated) 1-like 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007113.7 Reference GRCz11 Primary Assembly

      Range
      37449294..37462453 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001345991.9 → XP_001346027.4  serine/arginine repetitive matrix protein 1

      UniProtKB/TrEMBL
      A0A8M1PVE2, A0A8M3APV8
      Conserved Domains (1) summary
      cl02554
      Location:823 → 904
      PWWP; The PWWP domain, named for a conserved Pro-Trp-Trp-Pro motif, is a small domain consisting of 100-150 amino acids. The PWWP domain is found in numerous proteins that are involved in cell division, growth and differentiation. Most PWWP-domain proteins ...
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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    Research Materials