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    lsm4 LSM4 homolog, U6 small nuclear RNA and mRNA degradation associated [ Danio rerio (zebrafish) ]

    Gene ID: 393669, updated on 9-Dec-2024

    Summary

    Official Symbol
    lsm4provided by ZNC
    Official Full Name
    LSM4 homolog, U6 small nuclear RNA and mRNA degradation associatedprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040426-1652
    See related
    Ensembl:ENSDARG00000023852 AllianceGenome:ZFIN:ZDB-GENE-040426-1652
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:73057; zgc:77848
    Summary
    Predicted to enable U6 snRNA binding activity. Predicted to be involved in P-body assembly and spliceosomal snRNP assembly. Predicted to act upstream of or within mRNA splicing, via spliceosome. Predicted to be located in nucleus. Predicted to be part of U6 snRNP and spliceosomal tri-snRNP complex. Predicted to be active in P-body. Orthologous to human LSM4 (LSM4 homolog, U6 small nuclear RNA and mRNA degradation associated). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See lsm4 in Genome Data Viewer
    Location:
    chromosome: 11
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 11 NC_007122.7 (6859876..6868240, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 11 NC_007122.6 (6850037..6858401, complement)

    Chromosome 11 - NC_007122.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC101886158 Neighboring gene RAB3A, member RAS oncogene family, b Neighboring gene DEAD (Asp-Glu-Ala-Asp) box polypeptide 49 Neighboring gene kelch-like family member 26

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Clone Names

    • MGC73057

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables U6 snRNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in P-body assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within RNA processing IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within RNA splicing IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within mRNA processing IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within mRNA splicing, via spliceosome IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within nuclear-transcribed mRNA catabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in nuclear-transcribed mRNA catabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in spliceosomal snRNP assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in P-body IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of U6 snRNP IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    part_of ribonucleoprotein complex IEA
    Inferred from Electronic Annotation
    more info
     
    part_of spliceosomal complex IEA
    Inferred from Electronic Annotation
    more info
     
    part_of spliceosomal tri-snRNP complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    U6 snRNA-associated Sm-like protein LSm4
    Names
    LSM4 homolog, U6 small nuclear RNA associated

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_200696.1NP_956990.1  U6 snRNA-associated Sm-like protein LSm4

      See identical proteins and their annotated locations for NP_956990.1

      Status: PROVISIONAL

      Source sequence(s)
      BC059435
      UniProtKB/TrEMBL
      F6P7W7, Q6P6E4, Q6PC88
      Related
      ENSDARP00000037344.6, ENSDART00000037824.8
      Conserved Domains (1) summary
      cd01723
      Location:277
      LSm4; Like-Sm protein 4

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007122.7 Reference GRCz11 Primary Assembly

      Range
      6859876..6868240 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)