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    rnf10 ring finger protein 10 [ Danio rerio (zebrafish) ]

    Gene ID: 560444, updated on 9-Dec-2024

    Summary

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    Official Symbol
    rnf10provided by ZNC
    Official Full Name
    ring finger protein 10provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-2969
    See related
    Ensembl:ENSDARG00000079687 AllianceGenome:ZFIN:ZDB-GENE-030131-2969
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    fc22g07; wu:fc22g07; si:ch211-15b7.3
    Summary
    Predicted to enable transcription cis-regulatory region binding activity. Predicted to be involved in positive regulation of myelination and positive regulation of transcription by RNA polymerase II. Predicted to be located in cytoplasm. Orthologous to human RNF10 (ring finger protein 10). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See rnf10 in Genome Data Viewer
    Location:
    chromosome: 8
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 8 NC_007119.7 (41260394..41273768, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 8 NC_007119.6 (41252761..41266135, complement)

    Chromosome 8 - NC_007119.7Genomic Context describing neighboring genes Neighboring gene fumarylacetoacetate hydrolase domain containing 2A Neighboring gene zgc:152830 Neighboring gene POP5 homolog, ribonuclease P/MRP subunit Neighboring gene olfactomedin-like 2A

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. What makes a bad egg? Egg transcriptome reveals dysregulation of translational machinery and novel fertility genes important for fertilization. Cheung CT, et al. BMC Genomics, 2019 Jul 15. PMID 31307377, Free PMC Article
    2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables transcription cis-regulatory region binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in positive regulation of myelination IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in positive regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    E3 ubiquitin-protein ligase RNF10
    NP_001116727.1
    XP_005169141.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001123255.1 → NP_001116727.1  E3 ubiquitin-protein ligase RNF10

      Status: PROVISIONAL

      Source sequence(s)
      CR382384
      UniProtKB/TrEMBL
      A0A8M1NIH6, B0UXR5
      Related
      ENSDARP00000097766.3, ENSDART00000108518.5
      Conserved Domains (1) summary
      pfam13923
      Location:222 → 263
      zf-C3HC4_2; Zinc finger, C3HC4 type (RING finger)

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007119.7 Reference GRCz11 Primary Assembly

      Range
      41260394..41273768 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005169084.2 → XP_005169141.1  E3 ubiquitin-protein ligase RNF10 isoform X1

      UniProtKB/TrEMBL
      A0A8M2BGH7
      Conserved Domains (1) summary
      pfam13923
      Location:222 → 263
      zf-C3HC4_2; Zinc finger, C3HC4 type (RING finger)
    Nucleotide Protein Strain
    Heading Accession and Version

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