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    Exoc3l2 exocyst complex component 3-like 2 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 686809, updated on 27-Dec-2024

    Summary

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    Official Symbol
    Exoc3l2provided by RGD
    Official Full Name
    exocyst complex component 3-like 2provided by RGD
    Primary source
    RGD:1592539
    See related
    EnsemblRapid:ENSRNOG00000017448 AllianceGenome:RGD:1592539
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable SNARE binding activity. Predicted to be involved in exocyst localization and exocytosis. Predicted to act upstream of or within in utero embryonic development. Predicted to be part of exocyst. Orthologous to human EXOC3L2 (exocyst complex component 3 like 2). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Kidney (RPKM 71.2), Testes (RPKM 45.4) and 5 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Exoc3l2 in Genome Data Viewer
    Location:
    1q21
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (88241784..88273352)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (79113784..79145359)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (80372708..80404275)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene creatine kinase, M-type Neighboring gene microtubule affinity regulating kinase 4 Neighboring gene biogenesis of lysosomal organelles complex-1, subunit 3 Neighboring gene trafficking protein particle complex subunit 6A

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Highly variable penetrance of abnormal phenotypes in embryonic lethal knockout mice. Wilson R, et al. Wellcome Open Res, 2016. PMID 27996060, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables SNARE binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in exocyst localization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in exocytosis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in exocytosis IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within in utero embryonic development ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    part_of exocyst IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of exocyst IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    exocyst complex component 3-like 2; exocyst complex component 3-like protein 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001432576.1 → NP_001419505.1  exocyst complex component 3-like 2

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000001
      UniProtKB/TrEMBL
      A0A8I6A4S8

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      88241784..88273352
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039100835.2 → XP_038956763.1  exocyst complex component 3-like protein 2

      Related
      ENSRNOP00000087641.1, ENSRNOT00000110706.2
      Conserved Domains (1) summary
      cl19885
      Location:214 → 721
      Sec6; Exocyst complex component Sec6
    Nucleotide Protein Strain
    Heading Accession and Version

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    Research Materials