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    CG6664 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 39903, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG6664provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0036685
    Locus tag
    Dmel_CG6664
    See related
    AllianceGenome:FB:FBgn0036685
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG6664
    Summary
    Involved in motile cilium assembly and non-motile cilium assembly. Located in ciliary basal body. Orthologous to human CCDC6 (coiled-coil domain containing 6). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG6664 in Genome Data Viewer
    Location:
    73E4-73E4; 3-45 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (17012886..17016180, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (17005986..17009280, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene Ephexin Neighboring gene uncharacterized protein Neighboring gene mir-2500 stem loop Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A phylogenetic profiling approach identifies novel ciliogenesis genes in Drosophila and C. elegans. Dobbelaere J, et al. EMBO J, 2023 Aug 15. PMID 37317646, Free PMC Article
    2. Centromeric binding and activity of Protein Phosphatase 4. Lipinszki Z, et al. Nat Commun, 2015 Jan 6. PMID 25562660, Free PMC Article
    3. Genetic interaction of Lobe with its modifiers in dorsoventral patterning and growth of the Drosophila eye. Singh A, et al. Genetics, 2005 Sep. PMID 15976174, Free PMC Article
    4. Computation-based discovery of related transcriptional regulatory modules and motifs using an experimentally validated combinatorial model. Halfon MS, et al. Genome Res, 2002 Jul. PMID 12097338, Free PMC Article
    5. A large-scale RNAi screen reveals that mitochondrial function is important for meiotic chromosome organization in oocytes. Nieken KJ, et al. Chromosoma, 2023 Mar. PMID 36648541, Free PMC Article

    See all (32) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in establishment of meiotic spindle orientation ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in motile cilium assembly IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in non-motile cilium assembly IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in ciliary basal body IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in condensed chromosome ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in spindle pole ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG6664-PA
    CG6664-PB
    CG6664-PC

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      17012886..17016180 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_168710.3 → NP_730233.1  uncharacterized protein Dmel_CG6664, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_730233.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      C9QPB0, Q2PDZ3, Q8IHE7, Q9VVC8
      Related
      FBpp0075054
      Conserved Domains (2) summary
      pfam09755
      Location:4 → 310
      DUF2046; Uncharacterized conserved protein H4 (DUF2046)
      pfam13863
      Location:38 → 137
      DUF4200; Domain of unknown function (DUF4200)

    2. NM_140687.5 → NP_648944.1  uncharacterized protein Dmel_CG6664, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_648944.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      C9QPB0, Q2PDZ3, Q8IHE7, Q9VVC8
      Related
      FBpp0075053
      Conserved Domains (2) summary
      pfam09755
      Location:4 → 310
      DUF2046; Uncharacterized conserved protein H4 (DUF2046)
      pfam13863
      Location:38 → 137
      DUF4200; Domain of unknown function (DUF4200)

    3. NM_168709.4 → NP_730232.1  uncharacterized protein Dmel_CG6664, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_730232.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      C9QPB0, Q2PDZ3, Q8IHE7, Q9VVC8
      Related
      FBpp0075055
      Conserved Domains (2) summary
      pfam09755
      Location:4 → 310
      DUF2046; Uncharacterized conserved protein H4 (DUF2046)
      pfam13863
      Location:38 → 137
      DUF4200; Domain of unknown function (DUF4200)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8IHE7 Q8IHE7
    Q9VVC8 Q9VVC8

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