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    blnk B cell linker [ Danio rerio (zebrafish) ]

    Gene ID: 405764, updated on 9-Dec-2024

    Summary

    Official Symbol
    blnkprovided by ZNC
    Official Full Name
    B cell linkerprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040702-4
    See related
    Ensembl:ENSDARG00000042722 AllianceGenome:ZFIN:ZDB-GENE-040702-4
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Summary
    Predicted to be involved in cell surface receptor protein tyrosine kinase signaling pathway and intracellular signal transduction. Human ortholog(s) of this gene implicated in agammaglobulinemia and agammaglobulinemia 4. Orthologous to human BLNK (B cell linker). [provided by Alliance of Genome Resources, Dec 2024]
    Annotation information
    Annotation category: partial on reference assembly
    Orthologs
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    Genomic context

    See blnk in Genome Data Viewer
    Location:
    chromosome: 13
    Exon count:
    24
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 13 NC_007124.7 (50520563..50567658, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 13 NC_007124.6 (50203896..50252739, complement)

    Chromosome 13 - NC_007124.7Genomic Context describing neighboring genes Neighboring gene G protein-coupled receptor 137Ba Neighboring gene uncharacterized LOC101883869 Neighboring gene E3 SUMO-protein ligase ZBED1-like Neighboring gene cyclin J Neighboring gene microRNA 202 Neighboring gene ventral expressed homeobox

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_212838.1NP_998003.1  B-cell linker protein

      See identical proteins and their annotated locations for NP_998003.1

      Status: PROVISIONAL

      Source sequence(s)
      AF388205
      UniProtKB/TrEMBL
      Q8JI35
      Related
      ENSDARP00000062683.5, ENSDART00000062684.7
      Conserved Domains (1) summary
      cd09929
      Location:369489
      SH2_BLNK_SLP-76; Src homology 2 (SH2) domain found in B-cell linker (BLNK) protein and SH2 domain-containing leukocyte protein of 76 kDa (SLP-76)

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007124.7 Reference GRCz11 Primary Assembly

      Range
      50520563..50567658 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017358727.2XP_017214216.1  B-cell linker protein isoform X1

      UniProtKB/TrEMBL
      A0A8M6Z948