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    arl3l2 ADP ribosylation factor like GTPase 3, like 2 [ Danio rerio (zebrafish) ]

    Gene ID: 393692, updated on 9-Dec-2024

    Summary

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    Official Symbol
    arl3l2provided by ZNC
    Official Full Name
    ADP ribosylation factor like GTPase 3, like 2provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040426-1678
    See related
    Ensembl:ENSDARG00000015404 AllianceGenome:ZFIN:ZDB-GENE-040426-1678
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:73116
    Summary
    Predicted to enable GTP binding activity. Acts upstream of or within optomotor response and regulation of axon extension involved in axon guidance. Predicted to be located in centrosome. Predicted to be active in cytoplasm and microtubule cytoskeleton. Is expressed in brain; head; and visual system. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See arl3l2 in Genome Data Viewer
    Location:
    chromosome: 14
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 14 NC_007125.7 (909717..917067)
    105 previous assembly GRCz10 (GCF_000002035.5) 14 NC_007125.6 (891444..898809)

    Chromosome 14 - NC_007125.7Genomic Context describing neighboring genes Neighboring gene regulator of G protein signaling 14a Neighboring gene uncharacterized LOC103912050 Neighboring gene uncharacterized LOC137487551 Neighboring gene myozenin 3a

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Habenular commissure formation in zebrafish is regulated by the pineal gland-specific gene unc119c. Toyama R, et al. Dev Dyn, 2013 Sep. PMID 23749482, Free PMC Article
    2. Knockdown of unc119c results in visual impairment and early-onset retinal dystrophy in zebrafish. Rainy N, et al. Biochem Biophys Res Commun, 2016 May 13. PMID 27079236
    3. Tulp1 deficiency causes early-onset retinal degeneration through affecting ciliogenesis and activating ferroptosis in zebrafish. Jia D, et al. Cell Death Dis, 2022 Nov 17. PMID 36396940, Free PMC Article
    4. Transcriptome analysis of the zebrafish pineal gland. Toyama R, et al. Dev Dyn, 2009 Jul. PMID 19504458, Free PMC Article
    5. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC73116

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables GTP binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables GTP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in cilium assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within optomotor response IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of axon extension involved in axon guidance IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of axon extension involved in axon guidance IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in centrosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in microtubule cytoskeleton IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    ADP ribosylation factor like GTPase 3, like 2
    Names
    ADP-ribosylation factor-like 3, like 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_200719.1 → NP_957013.1  ADP ribosylation factor like GTPase 3, like 2

      See identical proteins and their annotated locations for NP_957013.1

      Status: PROVISIONAL

      Source sequence(s)
      BC059480
      UniProtKB/TrEMBL
      A0A8M1PBN5, Q6PC43
      Related
      ENSDARP00000008099.5, ENSDART00000021346.8
      Conserved Domains (1) summary
      cd04155
      Location:8 → 181
      Arl3; Arf-like 3 (Arl3) GTPase

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007125.7 Reference GRCz11 Primary Assembly

      Range
      909717..917067
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005169564.5 → XP_005169621.1  ADP ribosylation factor like GTPase 3, like 2 isoform X1

      UniProtKB/TrEMBL
      A0A140LG87, A0A8M2BGU1
      Related
      ENSDARP00000142265.1, ENSDART00000172777.2
      Conserved Domains (1) summary
      cd04155
      Location:8 → 180
      Arl3; Arf-like 3 (Arl3) GTPase
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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